DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synj and CVL1

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_001189654.1	Gene:	CVL1 / 817761	AraportID:	AT2G32010	Length:	594	Species:	Arabidopsis thaliana

Alignment Length:	635	Identity:	156/635 - (24%)
Similarity:	223/635 - (35%)	Gaps:	261/635 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly   427 KQQNISRFEEIFRQMWINNGNEVSKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDV 491
            |:..:|..:::.|: |.|..::..|..|.....||   :....|::....:...:..||.|
plant     7 KKSKLSWSKKMVRK-WFNIKSKTEKFQADVSLPQG---VEVEHRNSFSEREPCTIKKSKTE---- 63

  Fly   492 LLVGSTLSSELADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVA-----VGTYNVNGGK 551
                 .|:.....:||                   :|...|..||:..|.     |.|:||.|
plant    64 -----KLNKNWEQQAR-------------------QRKMNYENPRIIDVQNHSIFVATWNVAG-- 102

  Fly   552 HFRSIVFKDSLADWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTD 616
              ||.....:|.:||   |:.|                 |.|||.:||:|||.|||.|::.|. |
plant   103 --RSPPEDLNLDEWL---HSSA-----------------PADIYVLGFQEIVPLNAGNVLGAE-D 144

  Fly   617 N--AKLWAEELQKTI-------------------------------------------------- 629
            |  ||.|...::||:
plant   145 NGPAKKWHSLIRKTLNNLPGASSACHTPSPIPVPIAEIDADFSGSSRQKNETFFNRRSFQTPSVW 209

  Fly   630 ----------------------------------------------------------------- 629

plant   210 SMEENDPSISQPRLDRRFSVCDRVFFSHRPSDFDPSFRCGHRPSDYSRRPSDYSRPSDYYSRPSN 274

  Fly   630 -----------SRDND-----------------------------------YVLLTYQQLVGVCL 648
                       |.|:|                                   |.|:..:|:||:.|
plant   275 YSRPSDVSRWGSSDDDNGPGDSPSTFLNSPGSFLGSAANENGYRTPWNSSQYCLVASKQMVGIFL 339

  Fly   649 YIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAE--RN 711
            .|:::.|...|::::.:.||..||.|..||||:.:|..:||.||.||||.|..:||.:..|  ||
plant   340 TIWVKSELREHVKNMKVSCVGRGLMGYLGNKGSISISMLLHQTSFCFVCTHLTSGQKEGDELRRN 404

  Fly   712 ADYAEITRKLAFPMGRT---------LKSHDWVFWCGDFNYRIDMEKDELKECVRNGDLSTVLEF 767
            :|..||.:|..||..::         :..||.|.|.||.||||.:.....|..|...:...:||.
plant   405 SDVMEILKKTRFPRVQSSADEKSPENILQHDRVIWLGDLNYRIALSYRSAKALVEMQNWRALLEN 469

  Fly   768 DQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSD-----DYDTSEKQRAPAWTDRVLWRRRKALA 827
            ||||.||:.|:||..:.||:|.|.|||||...||     |....||:|.|||.||:||.
plant   470 DQLRIEQKRGHVFKGWNEGKIYFPPTYKYSNNSDRYAGGDLHPKEKRRTPAWCDRILWH------ 528

  Fly   828 EGDFAASAWNPGKLIH---YGRSELKQSDHRPVIAIIDAEIMEIDQQRRR 874
                       |:.:|   |.|.|.:.||||||..|..||:....::.:|
plant   529 -----------GEGLHQLSYVRGESRFSDHRPVYGIFSAEVESNHKRSKR 567

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	133/511 (26%)
		DUF1866	862..1008	CDD:286093	3/13 (23%)
CVL1	NP_001189654.1	EEP	17..582	CDD:412407	154/625 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	198	1.000	Domainoid score	I884
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770