Protein Alignment Synj and inpp5j

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_002934320.2
• Gene: inpp5j / 779554
• XenbaseID: XB-GENE-984978
• Length: 787
• Species: Xenopus tropicalis
• Alignment Length: 714
• Identity: 177/714 - (24%)
• Similarity: 291/714 - (40%)
• Gaps: 169/714 - (23%)

  Fly   505 RARILLPSNMLHAPTTVLRELCKR------YTEYVRPRMARV--AVGTYNVN-GGKHFRSIVFKD 560
            |:.:|.|......|.|..|....|      ..|.:||..|:.  :.|...|: .||.||..|.
 Frog   146 RSPVLSPRGSPDVPRTPHRAHTSRPQDQHPTPECIRPSPAKADKSQGDSTVDVAGKDFRIYVI-- 208

  Fly   561 SLADWLLDCHALARS--KALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAE 623
               .|.:.| |:..|  .:|:.:|..    |..:|::.||.:|:..:....:..|...:.  |:|
 Frog   209 ---TWNVGC-AVPPSDLTSLLCLNAR----DDKIDMFVIGLQEVNSMINKRLKDALFSDQ--WSE 263

  Fly   624 ELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVL 688
            .....:| ...|||::..::.|..|.::.:..|.|.:||:..||.:|||||..||||..:||..|
 Frog   264 VFMDVLS-PFSYVLVSSVRMQGCLLLVFSKYFHLPFLRDIQTDCTRTGLGGYWGNKGGVSIRLSL 327

  Fly   689 HGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAF--PMGRTLKSHDWVFWCGDFNYRI-DMEKD 750
            .|..:||:..|..|......:|..::..|.:...|  |:...:..||.|||.||.|:|| |::..
 Frog   328 FGHMVCFLNCHLPAHMENTDQRVDNFESILQLQQFQGPLANGVLDHDLVFWFGDLNFRIEDLDLH 392

  Fly   751 ELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWT 815
            .:|..::...|:.:.|.|||...:....|...|:||.:||.||||:|:.::.||||.|:|.||||
 Frog   393 FVKSAIQGNKLALLWEKDQLNMAKIFEPVLNGFMEGSLTFPPTYKFDVGTNTYDTSSKKRKPAWT 457

  Fly   816 DRVLWRRRKALAEGDFAASAWNPGK---------------LIHYG-RSELKQSDHRPVIAIIDAE 864
            ||:||:.:..:.:        :|.|               |:.|| ..:..:|||:||.||..
 Frog   458 DRILWKMKCPITQ--------SPAKQLGTISTRSKELSVTLLSYGSHMQYTESDHKPVSAIFS-- 512

  Fly   865 IMEIDQQRRRAVFEQVIRD--LGPPDSTIVVH----VLESS----------------------AT 901
             ::........:.:.::||  |.|.|:.::..    .::||                      |.
 Frog   513 -LQFASCLAAPLVQLLVRDEWLQPDDAHVIYRWCPGYMKSSWDWIGLYRVGFRHHKDYVSYVWAK 576

  Fly   902 GDED-------GPTIYDENVMSALITEL------SKMGEVTLVRYVEDTMWVTFRDGESALNASS 953
            .||:       ...::.|.::....:|.      :.:|  ||:. |.:...:...|.|:..:::|
 Frog   577 SDEETERGKHQHEVVFSEELLPKGTSEYLLGYFSNNLG--TLIG-VTEPFQICLPDSEAGSSSNS 638

  Fly   954 KKSIQVCGLDLILELKSKDWQHLVDSEIELCTTNTIPLCANPVEHAQLLQAITPELPQRPK-QPP 1017
            ..|          ..:.:|..|::                                 .||| :.|
 Frog   639 SDS----------SSEEEDSTHIL---------------------------------LRPKSRSP 660

  Fly  1018 TRPPARPPMPMSPKNSPRH---LPHVG-VISIVPKPAKPPMPPQPQSQPLIPSPLQPQVAPPRPP 1078
            :...||.|...||..:..|   ||:.. ..|..|.|.:...|...::|              |..
 Frog   661 SPASARSPRSRSPALARLHDLILPNTSRQKSRSPSPNRTKSPKHDRAQ--------------RSR 711

  Fly  1079 AMDTTPSSKS---QSPTELVSAS---SSTSSSGKTSPTAPAVLSGPPTPPRQMQSKQATPVSTP 1136
            :.::|..||.   |||..|.:.:   ...::.|:.......:|..|.:|..|:  |..|| |||
 Frog   712 SRESTRHSKGKRVQSPLVLQAITVPIVRPAAVGQGFSPQVGILPSPSSPKPQL--KLQTP-STP 772

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637
		INPP5c_Synj	538..863	CDD:197323	109/348 (31%)
		DUF1866	862..1008	CDD:286093	22/186 (12%)
inpp5j	XP_002934320.2	INPP5c_INPP5J-like	203..513	CDD:197328	104/333 (31%)
		SKICH	524..625	CDD:465482	16/103 (16%)
		alpha/beta hydrolases	652..>749	CDD:473884	26/143 (18%)