Protein Alignment Synj and Inpp5e

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_149125.1
• Gene: Inpp5e / 64436
• MGIID: 1927753
• Length: 647
• Species: Mus musculus
• Alignment Length: 408
• Identity: 115/408 - (28%)
• Similarity: 181/408 - (44%)
• Gaps: 84/408 - (20%)

  Fly   482 DNSKQEAIDVLLVGSTLSSELADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYN 546
            |:|...|....|:....:.::  |:|..|..::|.:...:..|...|   |...|...:.|.|:|
Mouse   251 DHSIHSARSFSLLAPIRTKDI--RSRSYLEGSLLASGALLGAEELAR---YFPDRNMALFVATWN 310

  Fly   547 VNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIM 611
            :.|.|...:     ||.::||                |:| .|:..|:|.||.:|
Mouse   311 MQGQKELPA-----SLDEFLL----------------PTE-ADYTQDLYVIGIQE---------- 343

  Fly   612 AASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGAT 676
              ...:.:.|...||:|:.  ..||||:......:.:.::||.:......:|....|.|.:....
Mouse   344 --GCSDRREWETRLQETLG--PQYVLLSSAAHGVLYMSLFIRRDLIWFCSEVEYSTVTTRIVSQI 404

  Fly   677 GNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAFP------------MGRTL 729
            ..|||..:.|...|||..|:.:||.:|..:||||..||:...:.||.|            .|...
Mouse   405 KTKGALGVSFTFFGTSFLFITSHFTSGDGKVAERLLDYSRTIQALALPRNVPDTNPYRSSAGDVT 469

  Fly   730 KSHDWVFWCGDFNYRID----------MEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFL 784
            ...|.|||.||||:|:.          .:|.|:       |:..:|:.|||.:|.:.|::|..|.
Mouse   470 TRFDEVFWFGDFNFRLSGGRVAVEAFLKQKPEV-------DVLALLQHDQLTREMKKGSIFRGFE 527

  Fly   785 EGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWN--PGKLIHYGRS 847
            |.||.|.|:||:|:..|.||::.|||.|::|||||::.|.   :||.....::  ||
Mouse   528 EAEIHFLPSYKFDIGKDTYDSTSKQRTPSYTDRVLYKSRH---KGDICPMKYSSCPG-------- 581

  Fly   848 ELKQSDHRPVIAIIDAEI 865
             :|.||||||..:...::
Mouse   582 -IKTSDHRPVYGLFQVKV 598

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	3/10 (30%)
		INPP5c_Synj	538..863	CDD:197323	103/348 (30%)
		DUF1866	862..1008	CDD:286093	0/4 (0%)
Inpp5e	NP_149125.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..80
		PHA03246	<14..166	CDD:223020
		3 X 4 AA repeats of P-X-X-P	52..243
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	101..131
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	177..196
		INPP5c_INPP5E-like	298..596	CDD:197329	104/352 (30%)