Protein Alignment Synj and inpp5e

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001096089.2
• Gene: inpp5e / 606579
• ZFINID: ZDB-GENE-050809-23
• Length: 635
• Species: Danio rerio
• Alignment Length: 429
• Identity: 123/429 - (28%)
• Similarity: 191/429 - (44%)
• Gaps: 86/429 - (20%)

  Fly   468 GARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARILLP------SNMLHAPTTVL---- 522
            |.|..:..:..||.|:   ..:|.::..:|....:.....:|.|      .|......:||
Zfish   212 GRRGRSERLHRNLSDS---RLLDTMVSDNTSVHSMKSTYSVLNPIRPRDVRNRSFLEGSVLGNGA 273

  Fly   523 ----RELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNN 583
                .||.:.:.|    |...:.:.|:|:.|.|.     ...:|.|.||
Zfish   274 LLGAEELDRYFPE----RRLGIYIATWNMQGEKG-----LPYNLDDLLL---------------- 313

  Fly   584 PSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVC- 647
            |:: .|...|:|.||.:|            ...:.:.|...||:|:   ..|.::.|....||.
Zfish   314 PTD-TDFAQDVYVIGVQE------------GCPDRREWEIRLQETL---GPYYVMLYAAAHGVLY 362

  Fly   648 LYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNA 712
            |.:::|.:......:|....|.|.:......|||..|.|...|||..||.:||.:|.|:|.||..
Zfish   363 LTVFVRRDLIWFCSEVEHATVTTRIISQIKTKGAVGIGFTFFGTSFLFVTSHFTSGDSKVYERIL 427

  Fly   713 DYAEITRKLAFPMG-------RTLKS-----HDWVFWCGDFNYRIDMEKDELKECVRNG---DLS 762
            ||.:|...||.|..       |:..|     .|.|||.||||:|::..:.:::..:..|   |:|
Zfish   428 DYNKIIEALALPRNLPDTNPYRSTTSDVTTRFDEVFWFGDFNFRLNKARGDVEAILNQGVGVDMS 492

  Fly   763 TVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALA 827
            .:|:.|||.:|.:.|::|..|.|..|.|.||||:|:..|.|||:.|||.|::|||:|:|.|:|
Zfish   493 PLLQHDQLTREMKEGSIFKGFQEASIHFPPTYKFDIGCDVYDTTTKQRTPSYTDRILYRNRQA-- 555

  Fly   828 EGDFAASAWNPGKLIHY-GRSELKQSDHRPVIAIIDAEI 865
                     :..::|.| ..|.:|.|||||||.:...::
Zfish   556 ---------DDIRVIKYTSCSSIKTSDHRPVIGMFQVKL 585

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	6/24 (25%)
		INPP5c_Synj	538..863	CDD:197323	107/341 (31%)
		DUF1866	862..1008	CDD:286093	0/4 (0%)
inpp5e	NP_001096089.2	INPP5c_INPP5E-like	285..583	CDD:197329	109/349 (31%)