Protein Alignment Synj and inpp5f

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_005156933.1
• Gene: inpp5f / 570007
• ZFINID: ZDB-GENE-041111-194
• Length: 1126
• Species: Danio rerio
• Alignment Length: 1261
• Identity: 259/1261 - (20%)
• Similarity: 452/1261 - (35%)
• Gaps: 409/1261 - (32%)

  Fly    40 ALLTQQETDVIRKQYTKVCDAY--GCLGALQLNAGESTVLFLVLVTGCVSMGKI-GDIEIFRITQ 101
            ::..:..||:: ..:..||...  |.:|.:||:.  ...|.|:|:.....:|:: ||.::::||:
Zfish    27 SMAVRPATDLL-LAWNPVCLGLVEGIIGKMQLHV--DLPLGLILIRQKALVGQLPGDHKVYKITK 88

  Fly   102 TTFVSLQNAAP------------------------------------------------------ 112
            ...:.|....|
Zfish    89 IVVIPLSEDEPQDLELELCKKHHFGINKPERITQSPDETKFLMKTLSQIKSNVGAPIKKKYSPAF 153

  Fly   113 ----NEDKISEVRKLL--------NSGTFYFAHTNASASASGASSYRFDITLCAQRRQQT----- 160
                |::|....|:||        :|.:||::.|             :|:|...||:.:.
Zfish   154 QVKENKEKERLERRLLDELYKIFMDSDSFYYSLT-------------YDLTNTVQRQGELGKSDQ 205

  Fly   161 ---QETDNRFFWNRMMHIHLMRFGIDCQS-----WLLQAMCGSVEVRTVYIGAKQA--------- 208
               :..|:|||||:    |:::..:|.|:     |::..:.|.|:|..:.:...::
Zfish   206 PLWKRVDDRFFWNK----HMIKDLVDLQAPQVDFWVIPIIQGFVQVEELVVNYNESSDEERSSPE 266

  Fly   209 ----------------RAAIISRLSCERAGTRFNVRGTNDEGYVANFVETEQVIYVDGDVTSYVQ 257
                            ..|:|||.|..|||.|:..||.:.:|:|||:|||||:|:|.....|:||
Zfish   267 TPLQEPTCVDDIHPRFTVALISRRSRHRAGMRYKRRGVDTDGHVANYVETEQLIHVHSHTLSFVQ 331

  Fly   258 TRGSVPLFWEQPGVQVGSHKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKEGE 322
            ||||||:||.|.|.:. :.:.::.:|...:...|..|.....:.|....::|     ||.....|
Zfish   332 TRGSVPVFWSQAGYRY-NPRPRIEKGERETMPYFASHFEKEVETYKKLVIIN-----LVDQNGRE 390

  Fly   323 AMLSNEFQRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFHASNGQVLRE 387
            .::.:.:.:...:..:.::.:|.||:|:.|||..|..:..|.:.|.....:..........|:.:
Zfish   391 KIIGDAYLKQVLLYNNPNLTYVSFDFHEHCRGMKFENVQTLTDAIYDIITDMRWAWVDQAGVICQ 455

  Fly   388 QFGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNIS-RFEEIFRQMWINNGNEVSK 451
            |.|:.|.||:|||||||.||..:....:..||:.|.:...:|.:. :...|::.||.|||:.:|:
Zfish   456 QEGIFRVNCMDCLDRTNVVQAAIARVIMEQQLKKLGVMPPEQPLPLKCYRIYQVMWANNGDTISR 520

  Fly   452 IYAGTGAIQG-----GSK-----LMDGARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRA 506
            .||||.|::|     |.:     :.||..||.|...|...|..:|..|| |::|..::.:
Zfish   521 QYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFRDAYRQAVID-LMMGHPVTED----- 579

  Fly   507 RILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVA--VGTY---------NVNGGKHFRSIVFKD 560
                    |::..:..:|..::..|..|....:|:  :.||         ..:||
Zfish   580 --------LYSIFSKEKEHEEKEKESQRGAQEQVSLLLQTYMQLLLPDDEKFHGG---------- 626

  Fly   561 SLADW-LLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEE 624
                | |:||     ..:|:|..:.                   |::...:::.|......:.||
Zfish   627 ----WALIDC-----DPSLIDATHK-------------------DVDVLLLLSNSAYYVAYYDEE 663

  Fly   625 LQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLH 689
            ..|.    |.|..|:.:.|.    .|.|.||  |.:               .|....|.:|.
Zfish   664 ADKV----NQYQRLSLEGLE----KIEIGPE--PTL---------------FGKPKYCCMRL--- 700

  Fly   690 GTSMCFVCAHFAAGQS-------QVAERNAD---------YAEITRKLAFPMGRTLKSHDWVFWC 738
                     |:..|::       :...||.:         .||:.|.....||
Zfish   701 ---------HYKNGETSGYFHTLRSVTRNPEDDGKDTLQCIAEMLRITKQAMG------------ 744

  Fly   739 GDFNYRIDMEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDY 803
                  :|::..|.|           ||....:..::...:.|:.::..:..........|.:.:
Zfish   745 ------LDVQVVEKK-----------LERRHSKPHEDIMGIQGKAVDQVLGSGLAQGKSFFLNKF 792

  Fly   804 DTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNP-GKLIHYGRSELKQSDHRPVIAIIDAEIME 867
            .|..::.....|:         :..|:|     .| |||..:.:.|:|.:..:|.:.:
Zfish   793 STLNQKVKQTKTN---------VNIGNF-----KPLGKLGTFSKPEVKVNFLKPNLHM------- 836

  Fly   868 IDQQRRRAVFEQVIRDLGPPDSTIVVHVLESSATGD----EDGPTIYDENVMSALIT----ELSK 924
                           :|...||::..|   .|.||.    :.||  :.|.:.|...:    |...
Zfish   837 ---------------NLWKSDSSLETH---DSNTGSGALKDHGP--HSEEISSDSDSYNSDEQPC 881

  Fly   925 MGEVTLVRYVEDTMWVTFRDGESALNASSKKSIQVCGLDLILELKSKDWQHLVDSEIEL--CTTN 987
            .|....|.||..:..:..........:.|..|:::.                |.|.|.:  |...
Zfish   882 SGSRENVDYVLPSCGIVASAPRLGSRSQSIGSVEIA----------------VPSVIRVTGCDEK 930

  Fly   988 TI----------PLCANPVEHAQLLQAITP------ELPQRPKQPPTRPPARPPMPMSPKNSPRH 1036
            |:          |..|:..|.|.|:...||      :..|..|        ..|:.:..:.:|
Zfish   931 TMDSLSVAADQSPGAASEAEEAILIDFGTPIDVYCHQFVQDAK--------TKPIEVFEEVAP-- 985

  Fly  1037 LPHVGVISIVPKPAKPPMPPQP-------QSQPLIPSPLQPQVAPPRPPA-------MDTTPSSK 1087
                     .|||..|.:|..|       .||..:|.|.|.:|......|       :.:..|..
Zfish   986 ---------APKPQGPQVPLAPDAKLGSSHSQNQLPRPSQLEVESNVHGANLLTVQPVGSATSCG 1041

  Fly  1088 SQSPTELVSASSSTSSSGK--TSPTA 1111
            ||...|.::..||..|:|.  .||.|
Zfish  1042 SQKSLEGITGPSSADSNGSRVVSPFA 1067

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	136/549 (25%)
		INPP5c_Synj	538..863	CDD:197323	55/353 (16%)
		DUF1866	862..1008	CDD:286093	30/171 (18%)
inpp5f	XP_005156933.1	COG5329	65..574	CDD:227637	132/532 (25%)
		hSac2	602..703	CDD:463592	29/175 (17%)