Protein Alignment Synj and inpp5ja

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_009303405.2
• Gene: inpp5ja / 569568
• ZFINID: ZDB-GENE-091117-4
• Length: 789
• Species: Danio rerio
• Alignment Length: 628
• Identity: 161/628 - (25%)
• Similarity: 255/628 - (40%)
• Gaps: 158/628 - (25%)

  Fly   593 DIYAIGFEEIVDLNASNIM-AASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEH 656
            |::.:|.:|:..:....:. |..||.   |:|....|:||.. |||:..|::.||.|.::.:..|
Zfish   246 DMFVVGLQEVNSMINKRLKDALFTDQ---WSELCMDTLSRFG-YVLVASQRMQGVFLLVFSKFCH 306

  Fly   657 APHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKL 721
            .|.:|.|.....:|||||..||||..:.|.::.|..:||:..|..|....:.:|..|:..|.::.
Zfish   307 LPFLRGVQTQSTRTGLGGYWGNKGGVSARMMVFGHPVCFLNCHLPAHMRNLEQRMEDFESILQQQ 371

  Fly   722 AFPMGRT--LKSHDWVFWCGDFNYRID-MEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEF 783
            .|.....  :..||.|||.||.|:||: .:...:|..:.|..|..:.|.|||...:::.:|...|
Zfish   372 QFEGSNAVGVLDHDVVFWFGDLNFRIEGYDIHVVKSAIENDKLPLLWEKDQLNMAKKSESVLEGF 436

  Fly   784 LEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRK----------ALAEGDFAASAWNP 838
            :||.:.|.||||:|:.:..||||.|:|.||||||:|||.|:          ||..|   .::|..
Zfish   437 IEGPLKFPPTYKFDVGTHTYDTSAKKRKPAWTDRILWRLRRTGSPVPSHNSALQRG---LTSWLG 498

  Fly   839 GK--------LIHYGRSELKQSDHRPVIAI--------IDAEIMEIDQQRRRAVFEQVIRDLGPP 887
            |.        ..|.|   ...|||:||.|:        :...::.::.::....|.
Zfish   499 GATRVSQHFYCSHMG---FTISDHKPVSALFSLHFPFKVTLPLVTLEVEKEWTKFS--------- 551

  Fly   888 DSTIVVHVLESSATGDEDGPTIYDENVMSALITELSKMG---EVTLVRYV----EDTMWVTF--- 942
            |:|:.:.:.........|...:|             |:|   ......||    |.:..|.|
Zfish   552 DATVKLTMAHGFQRSSWDWVGLY-------------KVGFKHHKDYAAYVWAKSEHSTQVVFSEE 603

  Fly   943 ---RD-GESALNASSKKSIQVCGLDLILEL------------KSKDWQHLVDSEIELCTTNTIPL 991
               || ||..|...|.....:.|:....::            :|:.....|.||.:    :|:.|
Zfish   604 DLPRDPGEYILGYYSNNMNSIAGVTEPFQVQLPMSTPPAPACRSRSDSSDVSSEDD----STLVL 664

  Fly   992 CA------NPVEHAQLLQAITPELPQRPKQPPTRPPARPPMPMSPKNSPRHLPHVGVISIVPKPA 1050
            .|      :|..|       :.:.....|:..:|.||.|.:..:|      ||.:..:|:.|:|.
Zfish   665 LAPSSRSPSPGNH-------SGKRHHHQKRQRSRSPAVPALSGTP------LPSLQSLSLCPRPR 716

  Fly  1051 KPPMPPQPQSQPLIPSPLQPQVAPPRPPAMDTTPSSKSQ--SPTELVSASSSTSS--------SG 1105
            ..|.                :.:.|||    :|.:.|.:  ||..|.|.|.|..|        :|
Zfish   717 DGPQ----------------KTSSPRP----STNAKKERLVSPDSLTSPSLSPLSPRSPGSPGNG 761

  Fly  1106 KTSPTA-PAVLSGPPTPPRQMQSKQATPVSTPTRQVGSPKDPI 1147
            .::|.| .|.:.|.|.|                .|:|.|.|.|
Zfish   762 ISAPEALVAAILGEPRP----------------AQIGKPGDVI 788

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637
		INPP5c_Synj	538..863	CDD:197323	97/299 (32%)
		DUF1866	862..1008	CDD:286093	28/177 (16%)
inpp5ja	XP_009303405.2	Herpes_BLLF1	<36..>168	CDD:282904
		INPP5c_INPP5J-like	214..528	CDD:197328	97/291 (33%)
		SKICH	539..633	CDD:465482	19/115 (17%)
		PRK12323	<627..>784	CDD:481241	42/209 (20%)