Protein Alignment Synj and sacm1la

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001038343.2
• Gene: sacm1la / 558940
• ZFINID: ZDB-GENE-060503-122
• Length: 586
• Species: Danio rerio
• Alignment Length: 487
• Identity: 147/487 - (30%)
• Similarity: 235/487 - (48%)
• Gaps: 94/487 - (19%)

  Fly    57 VCDAYGCLGALQLNAGESTVLFLVLVTGCVSMGKIGDI-----------EIFRITQT----TFVS 106
            :|   |.:|.::|.||    ::|:::|   ...|:||:           ::....:|    |.:.
Zfish    56 IC---GVMGTVRLVAG----MYLIVIT---RKRKVGDLFGHTVWKAVEFDVISYKKTILHLTDIQ 110

  Fly   107 LQNAAPNEDKISEVRKLLNSGTFYFAHTNASASASGASSYRFDITLCAQRRQQT----------Q 161
            :|:   |:..::.:..:||:..|||...             :|:|...||...|          :
Zfish   111 MQD---NKTFLTMINNVLNTDGFYFCTD-------------YDLTHTQQRLSNTSPDFQEMSLLE 159

  Fly   162 ETDNRFFWNRMMHIHLMRFGI---DCQSWLLQAMCGSVEVRTVYIGAKQARAAIISRLSCERAGT 223
            ..|.||.||.    :|:|..|   :...:....:.|.:.::...|..|.....||||.||.|||.
Zfish   160 RADQRFMWNG----NLLREIIAQPELHKFAFPVIHGFIVMKPCCINGKVFEWIIISRRSCFRAGV 220

  Fly   224 RFNVRGTNDEGYVANFVETEQVIYVDGDVTSYVQTRGSVPLFWEQ-PGVQVGSHKVKLSRGFETS 287
            |:.|||.:.||:.||||||||::..:....|:||||||:|.||.| |.::   :|.|.....:|:
Zfish   221 RYYVRGIDSEGHAANFVETEQIVQFNNARASFVQTRGSIPFFWSQRPNLK---YKPKPLISKDTN 282

  Fly   288 AAAFDRHMSMMRQR-------YGYQTVVNLLGSSLVGSKEGEAMLSNEFQRHHGMSAHKDVPHVV 345
                  ||..:|:.       ||.|.::|     ||..|..|..|...|.:......:..:.::.
Zfish   283 ------HMDGLRRHFESQVLIYGKQVILN-----LVNQKGSELPLEQAFAKMVSSMENGFIKYIA 336

  Fly   346 FDYHQECRGGNFSALAKLKERIVACGANYGVFH-ASNGQVLREQFGVVRTNCLDCLDRTNCVQTY 409
            ||:|:||....:..|..|.:.:......:|.|. :|:|:||.||.|..|:||:|||||||.:|:.
Zfish   337 FDFHKECSKMRWHRLQILVDAVSDMQEEFGYFMVSSDGKVLSEQSGTFRSNCMDCLDRTNVIQSL 401

  Fly   410 LGLDTLGIQLE---ALKMGGKQQNISRFEEIFRQMWINNGNEVSKIYAGTGAI-----QGGSK-- 464
            |...:|..||:   .|.:|.|.:..:.||:|::..|.:|.|..:|.||||||:     :.|.:
Zfish   402 LARRSLQSQLQRMGVLHVGQKIEEQADFEKIYKNAWADNANACAKQYAGTGALKTDFTRTGKRTH 466

  Fly   465 ---LMDGARSAARTIQNNLLDNSKQEAIDVLL 493
               :|||..|..|..:||..|..:|::||:.|
Zfish   467 WGLVMDGWNSMIRYYKNNFSDGFRQDSIDLFL 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	145/481 (30%)
		INPP5c_Synj	538..863	CDD:197323
		DUF1866	862..1008	CDD:286093
sacm1la	NP_001038343.2	COG5329	56..526	CDD:227637	147/487 (30%)
		Essential for phosphatidylinositol-4-phosphate phosphatase activity. /evidence=ECO:0000250|UniProtKB:Q9NTJ5	451..586		16/48 (33%)