Protein Alignment Synj and Inpp5b

DIOPT Version :9

• Sequence 1: NP_001246454.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_001094225.1
• Gene: Inpp5b / 362590
• RGDID: 1311511
• Length: 916
• Species: Rattus norvegicus
• Alignment Length: 646
• Identity: 186/646 - (28%)
• Similarity: 287/646 - (44%)
• Gaps: 123/646 - (19%)

  Fly   454 AGTGAIQGGSKLMDGARSAARTI---------------QNNLL--DNSKQEAIDVLLVGSTLSSE 501
            :|...|.||...:|.:|...|.:               :|:|.  :.||.|..| ::..||::
  Rat   170 SGFAPIGGGGYNVDSSRPNGRGLLPLDQSSGARCPDKPENSLTRQNRSKAEITD-MVRSSTIT-- 231

  Fly   502 LADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWL 566
            ::|:|.||.........|.|...|.::..||...:..|..||||||||...      |:.|..||
  Rat   232 VSDKAHILSMQKFGLRDTMVRSHLLQKEGEYTYIQNFRFFVGTYNVNGQSP------KECLRPWL 290

  Fly   567 LDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEELQKTISR 631
                              |.:...| |:|.:||:|: ||:........|...:.|.:.:.:::..
  Rat   291 ------------------SSDTKAP-DVYCVGFQEL-DLSKEAFFFHDTPKEEEWFKAVSESLHP 335

  Fly   632 DNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFV 696
            |..|..:...:|||:.|.:|::.|||.:|.:|..:.|.||:.|..||||..||||.||.||:|.|
  Rat   336 DAKYAKVKLIRLVGIMLLLYVKQEHAAYISEVEAETVGTGIMGRMGNKGGVAIRFQLHNTSICVV 400

  Fly   697 CAHFAAGQSQVAERNADYAEITRKLAF--------PMGRTLKSHDWVFWCGDFNYRI-DMEKDEL 752
            .:|.||...:...||.||.:|..::.|        |:  |:..||.:.|.||.|||| :::.:::
  Rat   401 NSHLAAHTEEYERRNQDYRDICSRMQFSQVDPSLPPL--TISKHDVILWLGDLNYRIEELDVEKV 463

  Fly   753 KECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDR 817
            |:.|......|:...|||:.:..|..||..|.||||||.||||||..||::|||||.|||||.||
  Rat   464 KKLVEEKAFHTLYAHDQLKIQVAAKTVFEGFTEGEITFQPTYKYDTGSDNWDTSEKCRAPAWCDR 528

  Fly   818 VLWRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIR 882
            ||||.:             |..:|.:.....||.|||:||.::.:..:..::::..|...|:::|
  Rat   529 VLWRGK-------------NISQLSYQSHMSLKTSDHKPVSSVFEIGVRVVNEELYRKTLEEIVR 580

  Fly   883 DLGP------PDSTI---------VVHVLESSATGDEDGPTIYDENVMSALITELSKMGEVTLVR 932
            .|..      |..|:         |.::...:||.     ||::..| ......::|..|.|..:
  Rat   581 SLDKMENANIPSVTLSKREFCFENVKYMQLQTATF-----TIHNGQV-PCEFEFINKPDEETYCK 639

  Fly   933 YVEDTMWVTFRDGESALNASSKKSIQV-------------CGLD-----LILEL-KSKDWQHLVD 978
                 .|:|.:.....|...|...|::             .|.|     |:|.| :.||:...|
  Rat   640 -----QWLTAKPSRGFLLPDSHVEIELELFVNKATATKLNSGKDTIEDILVLHLHRGKDYFLSV- 698

  Fly   979 SEIELCTTNTIPLC-ANPVEHAQLLQAITPELPQRPKQPPTRPPARPPMPMSPKNSPRHLP 1038
                  |.|.:|.| .:|:.....::....:||.:.....|....:.....|....|..:|
  Rat   699 ------TGNYLPSCFGSPIHTLCYMREPILDLPLKIVNELTLMTVQTADDRSQLEKPMEIP 753

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	123/333 (37%)
		DUF1866	862..1008	CDD:286093	33/180 (18%)
Inpp5b	NP_001094225.1	INPP5B_PH	6..150	CDD:293381
		INPP5c_INPP5B	268..561	CDD:197327	123/333 (37%)
		RhoGAP_OCRL1	695..915	CDD:239845	12/66 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810