Protein Alignment Synj and inppl1a

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_073778854.1
• Gene: inppl1a / 325179
• ZFINID: ZDB-GENE-030131-3904
• Length: 1274
• Species: Danio rerio
• Alignment Length: 1002
• Identity: 217/1002 - (21%)
• Similarity: 358/1002 - (35%)
• Gaps: 281/1002 - (28%)

  Fly   395 NCLDCLDRT---NCVQTYLGLDTLGIQLEALKMGGKQQNISRFEEIFRQMWINNGNE-----VSK 451
            |.|..|::|   :|.:.:..:|.:...||.|.....||:.|....:.:|.....|::     |:|
Zfish   194 NSLPHLNKTLLSSCKRLHGEVDKVLCGLEILSKVFDQQSASMVSRMIQQSMSQGGDQELEHLVTK 258

  Fly   452 IYAGTGAIQGGSK-----LMD-----GARSAARTIQNNLLDNSKQEA-IDVLL-----VGSTLSS 500
            :......:....|     |.|     .|.|...:|:|.::.....|. :||.|     :|.:...
Zfish   259 LAILKDLLSSIEKKALKALQDMSSSTPAISPLLSIRNKVIPVQTFEVKLDVYLADLTKIGKSQKY 323

  Fly   501 ELA--------------------------DRARILLPSNMLHAPTTVLRE--------------- 524
            .|:                          |:.|.|:.|..:.....::.|
Zfish   324 SLSVDVEGGKLVVMKKMKDAQEDWNTFTHDKIRQLIKSQRVQNKLGIVFEKEKDKSQRKDFIFAS 388

  Fly   525 ------LCK-------RYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSK 576
                  .|:       :::....|.|..:.:||:|:.      |:.....|..|:|   :....|
Zfish   389 AKKREAFCQLLQLMKNKHSNQDEPDMISIFIGTWNMG------SVPAPKPLGSWIL---SRGLGK 444

  Fly   577 ALVDVNNPSENVDHPVDIYAIGFEE--IVDLNASNIMAASTDNAKLWAEELQKTISR--DNDYVL 637
            .|.::     .|..|.|||..|.:|  :.|              |.|.|.|:.::..  |.:|..
Zfish   445 TLDEM-----AVTIPHDIYVFGTQENSVCD--------------KEWVETLRCSLKEYTDMEYKP 490

  Fly   638 LTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAA 702
            :..|.|..:.:.:.::.||...|..|.:..||||:....|||||..:.|:.:|||..||..|..:
Zfish   491 IAVQTLWNIKIVVLVKAEHENRISHVGMSSVKTGIANTLGNKGAVGVSFMFNGTSFGFVNCHLTS 555

  Fly   703 GQSQVAERNADYAEITRKLAFPMG-RTLKSHD------WVFWCGDFNYRIDMEKDELKECVRNGD 760
            |..::..||.:|.:|.|:|:  :| :.|.|.|      .:||.||.|||:||:..|:...:...:
Zfish   556 GNEKIHRRNQNYLDILRQLS--LGDKQLNSFDISLRFTHLFWFGDLNYRLDMDIQEILNYINRKE 618

  Fly   761 LSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRA-------PAWTDRV 818
            ...:|:.|||..|:|...:|..|.|.||::.|||:|:..|.|....:||:|       |:|.||:
Zfish   619 FDPLLKVDQLNLEREKNKIFLRFAEEEISYPPTYRYERGSRDTYVWQKQKATGMRTNVPSWCDRI 683

  Fly   819 LWRRRKALAEGDFAASAWNPGKLIHYG-RSELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIR 882
            ||   |:..|.....::        || ..::..|||.||....:.           .|..|.:.
Zfish   684 LW---KSYPETHIVCNS--------YGCTDDIVTSDHSPVFGTFEV-----------GVTSQFVS 726

  Fly   883 DLGPPDSTIVVHV------------------LESSATGDEDGPTIYDENVMSALITELSKMGEVT 929
            ..|.|.|:...::                  :|..:|..|:....|:.:..|:......::|
Zfish   727 KKGLPKSSEQAYIEFENIEAIVKTASRTKFFIEFYSTCLEEFKKSYENDTQSSDNVNFLRVG--- 788

  Fly   930 LVRYVEDTMWVTFRDGESALNASSKKSIQVCGLDLILELKSKDWQHLVDSEIELCTTNTIPLCAN 994
                     |            |||   |:..|..||    .|.::|.|..:.|    |:.....
Zfish   789 ---------W------------SSK---QLTTLKPIL----SDIEYLQDQHLLL----TVKSLDG 821

  Fly   995 PVEHAQLLQAITPELPQRPKQPPT------------RPPARPPMPMSPKNSPRHLPHVGVISI-- 1045
            ...:.:.:.|:...:....:|..|            |...|..:|.....:...|  ...||:
Zfish   822 YESYGECVLALKSMIGSTAQQFHTYLSHRGEETGNIRGSMRVRVPSERMGTRERL--YEWISVDK 884

  Fly  1046 --VPKPAKPPMPPQPQSQPLIPSPLQPQVAPPRPPAMD--TTPSSKSQSPTELVSASSSTSSSGK 1106
              :..|....:||:.....:.|:.....:.......:.  :....||.:.....:...:|.:.||
Zfish   885 DDMGGPKGRTLPPRSSHDYVKPTSSSSSIRKHGSAELSRVSEEGEKSSTSRHTHTKEENTHNRGK 949

  Fly  1107 TSP-----------------------------TAPAVLSGPPTPPRQMQSKQATPVSTPTRQVGS 1142
            ..|                             .|..:|.|...||  :.:|...|   |...||.
Zfish   950 QDPFESDATTCKNSFNNPAYYILEGVPNQSAALASDILPGSALPP--LANKTTAP---PAGSVGK 1009

  Fly  1143 PKDPIPSDT--AYETASNIYEEIQEDVPAP---RHPPPAG----PPPVIGAPMGPPPPLP----- 1193
            .|.|..|..  .::|:......|.|:..:.   ...|.||    |||..     ||||||
Zfish  1010 SKPPSGSSAQGRWQTSGRSVRPISEEGSSEDDGNIGPHAGSLNRPPPDF-----PPPPLPKAALE 1069

  Fly  1194 ---NRRGPPPIPN--RSGNAPPLPTRP 1215
               |..|.|.:.:  ..|..|| |::|
Zfish  1070 MSENSFGKPRVFSDLADGKIPP-PSKP 1095

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	26/116 (22%)
		INPP5c_Synj	538..863	CDD:197323	101/343 (29%)
		DUF1866	862..1008	CDD:286093	25/163 (15%)
inppl1a	XP_073778854.1	None