DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Synj and SPAC9G1.10c

DIOPT Version :9

Sequence 1:	NP_001246454.1	Gene:	Synj / 37517	FlyBaseID:	FBgn0034691	Length:	1218	Species:	Drosophila melanogaster
Sequence 2:	NP_593565.1	Gene:	SPAC9G1.10c / 2542329	PomBaseID:	SPAC9G1.10c	Length:	1191	Species:	Schizosaccharomyces pombe

Alignment Length:	448	Identity:	132/448 - (29%)
Similarity:	211/448 - (47%)	Gaps:	90/448 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly   473 ARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARILLPSNMLHAPTTVLRELCKRYTEYVRPRM 537
            |:.:|...:.:|..:..|.|::|..|::|:.                       .|:.||.....
pombe   747 AKRLQVVSMASSVVKFWDGLMMGDWLATEMR-----------------------SRFPEYSNFTD 788

  Fly   538 ARVAVGTYNVNGGKHFRSIVFKDSLADWLLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEI 602
            ..:.:.::|....|.          :|  ||...:..|...:.:.:..    :| ||...||:|:
pombe   789 VSILICSWNAGASKP----------SD--LDSDTIGASMIPMMIRDNG----YP-DIVVFGFQEL 836

  Fly   603 VD-----LNASNIMAASTDNA------------KLWAEELQK---TISRDNDYVLLTYQQLVGVC 647
            ||     |.|.:|::.|:...            :||.|:|:.   .:|.::||.:|..:.|||:.
pombe   837 VDLENKRLTARSILSKSSSKGGSSNSANISSQYRLWREKLESEMMRVSSNDDYQVLVCENLVGLF 901

  Fly   648 LYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNA 712
            ..::::.:....||.:....|||||||..|||||..:||::..||.|.|..|.|||||..|.||.
pombe   902 SCVFVKNKLQSKIRMLQSTTVKTGLGGLHGNKGAIVVRFLVDDTSYCIVNCHLAAGQSNKAARNN 966

  Fly   713 DYAEITRKLA-FPM---------------GRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNGDL 761
            |.|.|....: ||.               |..:..|:.....||.||||:..:.:..:.::..|:
pombe   967 DLATILDNASLFPENDETDQLNTFVGGGDGSLIMDHEVCVLHGDLNYRINTLRPKALDLIKKNDI 1031

  Fly   762 STVLEFDQL--RKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRK 824
            .|:|:.|||  .:::.||.....|.|.||||.||||||:.|:.||:|||:|.|||.||:.:|
pombe  1032 KTLLQSDQLLVERKRNAGFRLRTFTEPEITFAPTYKYDVHSEQYDSSEKKRVPAWCDRICYR--- 1093

  Fly   825 ALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIR 882
              ...|:.::.       :|.|.|||.||||||.|:|.::...::.|.:.:.::.|.|
pombe  1094 --GSPDYISAE-------NYTRYELKASDHRPVSALIHSKAKMVNAQSQGSTWDVVKR 1142

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_001246454.1	Syja_N	61..353	CDD:280532
		INPP5c_Synj	538..863	CDD:197323	118/362 (33%)
		DUF1866	862..1008	CDD:286093	3/21 (14%)
SPAC9G1.10c	NP_593565.1	COG5411	281..794	CDD:227698	11/69 (16%)
		IPPc	787..1126	CDD:214525	118/367 (32%)
		UBA_TAP-C_like	1161..1186	CDD:270459
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5411
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810