| Sequence 1: | NP_001246454.1 | Gene: | Synj / 37517 | FlyBaseID: | FBgn0034691 | Length: | 1218 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_766027.2 | Gene: | Inpp5j / 170835 | MGIID: | 2158663 | Length: | 1003 | Species: | Mus musculus |
| Alignment Length: | 594 | Identity: | 148/594 - (24%) |
|---|---|---|---|
| Similarity: | 230/594 - (38%) | Gaps: | 153/594 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 593 DIYAIGFEEIVDLNASNIM-AASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEH 656
Fly 657 APHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKL 721
Fly 722 AF--PMGRTLKSHDWVFWCGDFNYRID-MEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEF 783
Fly 784 LEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKL---IHYG 845
Fly 846 RSELKQ--SDHRPVIAII--------DAEIMEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLES-S 899
Fly 900 ATGDEDGPTIY---------------------DENVMSALITELS---KMGEVTLVRY------- 933
Fly 934 --VEDTMWVTFRDGESALNASSKKSIQVCGLDLILELKSKDWQHLVDSEIELCTTNTIPLCANPV 996
Fly 997 EHAQLLQAITPELPQRPKQPPTRPPARPPMPMSPKNSPRHLPHVGVISIVPKPAKPP-------- 1053
Fly 1054 -MPPQPQSQPLIPSPLQPQVAPPRPPAMDTTPSSKSQSPTELVSASSSTSSSGKTSPTA-PAVLS 1116
Fly 1117 GPPTPPRQM 1125 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Synj | NP_001246454.1 | Syja_N | 61..353 | CDD:280532 | |
| INPP5c_Synj | 538..863 | CDD:197323 | 92/286 (32%) | ||
| DUF1866 | 862..1008 | CDD:286093 | 25/179 (14%) | ||
| Inpp5j | NP_766027.2 | Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1..110 | ||
| RSXSXX motif 1 | 6..11 | ||||
| PHA03247 | <50..337 | CDD:223021 | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 147..414 | ||||
| SH3-binding. /evidence=ECO:0000255 | 346..351 | ||||
| RSXSXX motif 2 | 351..356 | ||||
| INPP5c_INPP5J-like | 420..727 | CDD:197328 | 92/278 (33%) | ||
| Catalytic. /evidence=ECO:0000255 | 422..725 | 92/276 (33%) | |||
| Required for ruffle localization | 726..837 | 16/120 (13%) | |||
| SKICH | 738..836 | CDD:375315 | 15/107 (14%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 839..1003 | 40/193 (21%) | |||
| RSXSXX motif 3 | 871..876 | 3/7 (43%) | |||
| RSXSXX motif 4 | 882..887 | 0/4 (0%) | |||
| RSXSXX motif 5 | 908..913 | 1/4 (25%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 1 | 0.930 | - | - | C167836224 | |
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_COG5411 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 1 | 1.000 | - | - | ||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.740 | |||||