Protein Alignment Synj and Synj

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_061517465.1
• Gene: Synj / 1280512
• VectorBaseID: AGAMI1_004276
• Length: 1255
• Species: Anopheles gambiae
• Alignment Length: 1309
• Identity: 835/1309 - (63%)
• Similarity: 965/1309 - (73%)
• Gaps: 147/1309 - (11%)

  Fly     1 MAMSKVIRVLEKSIAPSPHSVLLEHRNKSDSILFESHAVALLTQQETDVIRKQYTKVCDAYGCLG 65
            |||||..||||||..|||||||||||||.:::||||.|||:|:.|||:::|||||||.|||||||
Mosquito     1 MAMSKGFRVLEKSKPPSPHSVLLEHRNKPETLLFESQAVAVLSAQETEIVRKQYTKVLDAYGCLG 65

  Fly    66 ALQLNAGESTVLFLVLVTGCVSMGKIGDIEIFRITQTTFVSLQNAAPNEDKISEVRKLLNSGTFY 130
            .||||||:|::|:||:||||.|:|||.|.||||||||.|||||....||||::|:||:|||||||
Mosquito    66 VLQLNAGDSSLLYLVMVTGCFSVGKILDSEIFRITQTQFVSLQYQPTNEDKVAEIRKVLNSGTFY 130

  Fly   131 FAHTNASASASG------ASSYRFDITLCAQRRQQTQETDNRFFWNRMMHIHLMRFGIDCQSWLL 189
            |:.:|.:.|..|      |..:.||:||.||||::|:|||||||||||:.|||:|||::|..|||
Mosquito   131 FSFSNVAGSGGGGTGPTIAQPFGFDVTLSAQRRRRTRETDNRFFWNRMLFIHLLRFGVECNFWLL 195

  Fly   190 QAMCGSVEVRTVYIGAKQARAAIISRLSCERAGTRFNVRGTNDEGYVANFVETEQVIYVDGDVTS 254
            :|||||||:||||.|:|||||||||||||||||||||||||||||.|||||||||.||:|.::||
Mosquito   196 KAMCGSVEIRTVYAGSKQARAAIISRLSCERAGTRFNVRGTNDEGCVANFVETEQCIYLDNEITS 260

  Fly   255 YVQTRGSVPLFWEQPGVQVGSHKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSK 319
            |||||||||||||||||||||||||||||||.|.:||||||..|:.|||.|.:|||||:||:|||
Mosquito   261 YVQTRGSVPLFWEQPGVQVGSHKVKLSRGFEASRSAFDRHMRTMKARYGQQAIVNLLGTSLIGSK 325

  Fly   320 EGEAMLSNEFQRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVFHASNGQV 384
            ||||||||||||||..|.|.||||:||||||||||||..||:||:::|.|..|::|:|:|....|
Mosquito   326 EGEAMLSNEFQRHHRESEHTDVPHLVFDYHQECRGGNTVALSKLRQKIDATCADFGMFYAIGDAV 390

  Fly   385 LREQFGVVRTNCLDCLDRTNCVQTYLGLDTLG--IQLEALKMGGKQQNISRFEEIFRQMWINNGN 447
            .|||.|.:|||||||||||||||||:||:.|.  |.|.|.....|||..|||||:||||||||||
Mosquito   391 YREQRGAIRTNCLDCLDRTNCVQTYIGLEMLNEQITLMAALADKKQQMSSRFEEVFRQMWINNGN 455

  Fly   448 EVSKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARILLPS 512
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mosquito   456 EVSKIYAGTGAIQGGSKLMDGARSAARTIQNNLLDNSKQEAIDVLLVGSTLSSELADRARILLPS 520

  Fly   513 NMLHAPTTVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHFRSIVFKD-SLADWLLDCHALARSK 576
            |||||||.||||:||||.|||.|.:.|||.|||||||||||||:.:|| ||||||||||.||||:
Mosquito   521 NMLHAPTPVLREMCKRYEEYVNPLVFRVACGTYNVNGGKHFRSVAYKDVSLADWLLDCHRLARSR 585

  Fly   577 ALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQ 641
            :|||.:...::.:.||||:||||:||||||||||:|||:||||.|||||||.:|||.:|||||||
Mosquito   586 SLVDFSQVDDSNEPPVDIFAIGFQEIVDLNASNIVAASSDNAKAWAEELQKVVSRDREYVLLTYQ 650

  Fly   642 QLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQ 706
            |||||||||||||:||.:||||||||||||||||||||||.||||||||||:|||||||||||||
Mosquito   651 QLVGVCLYIYIRPQHAQYIRDVAIDCVKTGLGGATGNKGAAAIRFVLHGTSICFVCAHFAAGQSQ 715

  Fly   707 VAERNADYAEITRKLAFPMGRTLKSHDWVFWCGDFNYRIDMEKDELKECVRNG--DLSTVLEFDQ 769
            ||||||||||||||:||||||:|||||::||||||||||||:||||:|.::..  ||:.||::||
Mosquito   716 VAERNADYAEITRKIAFPMGRSLKSHDYIFWCGDFNYRIDMDKDELREALKQSPHDLTAVLQYDQ 780

  Fly   770 LRKEQEAGNVFGEFLEGEITFDPTYKYDLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAAS 834
            ||.:|.||:||.|||||||:|.|||||||||||||||||.|||||||||||||||...:.| ...
Mosquito   781 LRIQQNAGSVFNEFLEGEISFPPTYKYDLFSDDYDTSEKCRAPAWTDRVLWRRRKQSPDAD-RHP 844

  Fly   835 AWNPGKLIHYGRSELKQSDHRPVIAIIDAEIMEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLESS 899
            .||||:|:||||:||||||||||||:||.|:..||.:||..||..|||||||||.||::.....|
Mosquito   845 GWNPGRLVHYGRAELKQSDHRPVIAMIDIEVHYIDPERRSTVFGDVIRDLGPPDGTILIQACSPS 909

  Fly   900 A----TGDEDGPTIYDENVMSALITELSKMGEVTLVRYVEDTMWVTFRDGESALNASSKKSIQVC 960
            |    :||||..:|||||:|:|||.||:::|||||||:|.||||||||||:|||.|:.|:|:.||
Mosquito   910 AAGTDSGDEDEGSIYDENLMAALIQELTQIGEVTLVRFVGDTMWVTFRDGQSALTAAQKRSVLVC 974

  Fly   961 GLDLILELKSKDWQHLVDSEIELCTTNTIPLCANPVEHAQLLQAITPELPQRPKQPPT------- 1018
            |:.|.::||:::|...|:.||.|||.||:..|..............||:|.|||.||:
Mosquito   975 GVQLSIKLKTENWVEQVEKEILLCTPNTVSFCDGSQTGGDYNSLGIPEIPARPKSPPSVPQQPSA 1039

  Fly  1019 --RPPARPPMPMSPKNSPRHL----------PHVGVISIVP------KPAKPPMPPQPQSQPLIP 1065
              .||:|||:|.||:.||:|.          |..||||:.|      |..:||..|     |.:|
Mosquito  1040 RPGPPSRPPLPKSPQASPKHQPQQQQHHHHHPRAGVISLGPEILMASKLQQPPKVP-----PAVP 1099

  Fly  1066 SPLQPQVAPPRPPAMDTTPSSKSQSPTELVSASSSTSSSGKTSPTAPAVLSGPPTPPRQMQSKQA 1130
            .|      |.||     ||      |.|..::||...||             |...|.|
Mosquito  1100 CP------PQRP-----TP------PVEEYASSSPVPSS-------------PTHGPGQ------ 1128

  Fly  1131 TPVSTPTRQVGSPKDPIPSDTAYETASNIYEEIQEDVPAPRHP--PPAGPP-------------- 1179
                   :|.||...| |.||     ..|||||.:|:|.|..|  ||..||
Mosquito  1129 -------QQPGSSNLP-PVDT-----GAIYEEINDDIPVPEQPRGPPPPPPRSDVYDLDVVSNST 1180

  Fly  1180 -----------------------------------PVIGAPMGPPPPLPNRRG-PPPIPNRSGNA 1208
                                               |..|.|.|.|||||.||| |||||||||..
Mosquito  1181 NSSSKSAPTKSSPPGTSGSSGAGSPSSTTGGNGVLPPSGPPKGAPPPLPMRRGAPPPIPNRSGGP 1245

  Fly  1209 PPLPTRPAN 1217
            ||||.||.|
Mosquito  1246 PPLPARPNN 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	326/439 (74%)
		INPP5c_Synj	538..863	CDD:197323	255/327 (78%)
		DUF1866	862..1008	CDD:286093	76/149 (51%)
Synj	XP_061517465.1	None