DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Synj and SH2D1B

DIOPT Version :9

Sequence 1:NP_001246454.1 Gene:Synj / 37517 FlyBaseID:FBgn0034691 Length:1218 Species:Drosophila melanogaster
Sequence 2:NP_444512.2 Gene:SH2D1B / 117157 HGNCID:30416 Length:132 Species:Homo sapiens


Alignment Length:75 Identity:19/75 - (25%)
Similarity:28/75 - (37%) Gaps:28/75 - (37%)


- Green bases have known domain annotations that are detailed below.


  Fly   340 DVPHVVFDYH-----QECRGGNFSALAKLKERIVACGANYGVFHASNGQVLREQFGVVRTNCLDC 399
            |:|:    ||     |:|.      ...|||.:   ..|:         :||:...:....|| |
Human     2 DLPY----YHGRLTKQDCE------TLLLKEGV---DGNF---------LLRDSESIPGVLCL-C 43

  Fly   400 LDRTNCVQTY 409
            :...|.|.||
Human    44 VSFKNIVYTY 53

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
SynjNP_001246454.1 Syja_N 61..353 CDD:280532 5/17 (29%)
INPP5c_Synj 538..863 CDD:197323
DUF1866 862..1008 CDD:286093
SH2D1BNP_444512.2 SH2_SAP1 1..103 CDD:198205 19/75 (25%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C165146121
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5411
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.830

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