Protein Alignment Synj and Fig4

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: NP_598760.1
• Gene: Fig4 / 103199
• MGIID: 2143585
• Length: 907
• Species: Mus musculus
• Alignment Length: 600
• Identity: 143/600 - (23%)
• Similarity: 252/600 - (42%)
• Gaps: 157/600 - (26%)

  Fly    15 APSPHSVL-LEHRNKSDSILFESHAVALLTQQE-------------TDVIRKQYT---KVCDAYG 62
            |.:.:.|| ::.....|.::.:...|  .||||             |.:.:|..:   :...|:|
Mouse    32 AETKYRVLKIDRTEPKDLVVIDDRHV--YTQQEVRELLGRLDLGNRTKMSQKGSSGLFRAVSAFG 94

  Fly    63 CLGALQLNAGESTVLFLVLVTGCVSMGKIGDIEIFRITQTTFVSLQN-----AAPNEDKISEVRK 122
            .:|.::...|    .::||:|....|..||...|::|..|:.:.:.|     :.|:|.:...:.:
Mouse    95 VVGFVRFLEG----YYIVLITKRRKMADIGGHAIYKIEDTSMIYIPNDSVRISHPDEARYLRIFQ 155

  Fly   123 LLN-SGTFYFAHTNASASASGASSYRFDIT--------LCAQRRQQTQETDN------------- 165
            .:: |..|||::     |...:.|.::::|        |.::..:..||:.:
Mouse   156 NVDLSSNFYFSY-----SYDLSHSLQYNLTVLRMPLEMLKSETSKACQESFDIFEDEGLITQGGS 215

  Fly   166 -----------RFFWNRMMHIHLMRFGIDCQSWLL---QAMCGSVEV----RTVYIGAKQARAAI 212
                       ::.||..: :.:::..:. :.|||   ...||..::    |.||:       .:
Mouse   216 GVFGISSEPYMKYVWNGEL-LDIIKNTVH-RDWLLYIIHGFCGQSKLLIYGRPVYV-------TL 271

  Fly   213 ISRLSCERAGTRFNVRGTNDEGYVANFVETEQVI-------YVDGDVTSYVQTRGSVPLFWEQP- 269
            |:|.|...|||||..||.|.||.|||.|||||::       :..|..:||||.||||||||.|.
Mouse   272 IARRSSRFAGTRFLKRGANCEGDVANEVETEQILCDASVMSFTAGSYSSYVQVRGSVPLFWSQDI 336

  Fly   270 GVQVGSHKVKLSRG--FETSAAAFDRHMSMMRQRYGYQTVVNLLGSSLVGSKE---GEAMLSNEF 329
            ...:....:.|.:.  |...||.   |...|.||:|...::    .:||..:|   .|.:||.|.
Mouse   337 STMMPKPPITLDQADPFAHVAAL---HFDQMLQRFGSPIII----LNLVKEREKRKHERILSEEL 394

  Fly   330 -----QRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANYGVF------------ 377
                 ..:..:.....:.::.:|..:..:....:.|.:|.....:.....|.|
Mouse   395 VAAVTYLNQFLPPEHTIVYIPWDMAKYTKSKLCNVLDRLNVIAESVVKKTGFFVNRPDSYCSILR 459

  Fly   378 -----HASNGQVL---REQFGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNISRF 434
                 :...|.|:   |.|.|::||||:|||||||..|..:|...|..||.:|.:..| .|: :|
Mouse   460 PDEKWNELGGHVIPTGRLQTGILRTNCVDCLDRTNTAQFMVGKCALAYQLYSLGLIDK-PNL-QF 522

  Fly   435 E----EIFRQMWINNGNEVSKIYAGTGAIQGGSKLM-----------------DGARSAARTIQN 478
            :    .:|.:::.::|:.:|..|       |||:|:                 |..::.:|...|
Mouse   523 DTDAVRLFEELYEDHGDTLSLQY-------GGSQLVHRVKTYRKIAPWTQHSKDIMQTLSRYYSN 580

  Fly   479 NLLDNSKQEAIDVLL 493
            ...|..:|::|::.|
Mouse   581 AFSDADRQDSINLFL 595

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	130/535 (24%)
		INPP5c_Synj	538..863	CDD:197323
		DUF1866	862..1008	CDD:286093
Fig4	NP_598760.1	Syja_N	93..423	CDD:460545	87/354 (25%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	707..790