Protein Alignment Synj and inpp5f

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_031761377.1
• Gene: inpp5f / 100379801
• XenbaseID: XB-GENE-1008490
• Length: 1106
• Species: Xenopus tropicalis
• Alignment Length: 1344
• Identity: 274/1344 - (20%)
• Similarity: 473/1344 - (35%)
• Gaps: 405/1344 - (30%)

  Fly    19 HSVLLEHRNKSDSILFESHAVALLTQQETDVIRKQYTKVCDAY--GCLGALQLNAGESTVLFLV- 80
            |.:|    .:.:|.|:.|.....||.:....:...:..:|...  |.:|.:||:......|.|:
 Frog     9 HYIL----QRGESALWCSRQDGSLTSRAATDLLLAWNPICLGLVEGIIGKVQLHTDLPWWLLLIR 69

  Fly    81 ------LVTGCVSMGKIG-------------DIEI-------------FRITQT----------- 102
                  ::.|...:.||.             |:|:             .:|||:
 Frog    70 QKSLIGILPGGHEIYKINKIAAIPLSGAEPQDLELELCKKHHFGINKPEKITQSPDDSKFLMKTL 134

  Fly   103 TFVSLQNAAPNEDKISE-------VRKLL--------NSGTFYFAHTNASASASGASSYRFDITL 152
            |.:....:||.:.|:.|       .|:||        :|.:||:             |:.:|:|.
 Frog   135 TQIKSNVSAPAKKKVKESKEKERLERRLLEELFKMFMDSDSFYY-------------SWTYDLTS 186

  Fly   153 CAQRRQQT--------QETDNRFFWNRMMHIHLMRFGIDCQS-----WLLQAMCGSVEVRTVYIG 204
            ..||:...        |..|:|||||:    |:::..||.:.     |:|..:.|.|::..:.:.
 Frog   187 SVQRQSSREKSDLLLWQTVDDRFFWNK----HMIQDLIDIKDPQGSVWILPIIQGFVQIEELVVN 247

  Fly   205 AKQA-------------------------RAAIISRLSCERAGTRFNVRGTNDEGYVANFVETEQ 244
            ..::                         ..|:|||.|..|||.|:..||.:..|:|||:|||||
 Frog   248 YNESSDDEKSSPETPPQEPTCVDDIHPRFMVALISRRSRHRAGMRYKRRGVDKFGHVANYVETEQ 312

  Fly   245 VIYVDGDVTSYVQTRGSVPLFWEQPGVQVGSHKVKLSRGFETSAAAFDRHMSMMRQRYGYQTVVN 309
            :|:|.....|:||||||||:||.|.|.:. :.:.:|.:..:.::..|..|.:.....|..|.::|
 Frog   313 LIHVHNHTLSFVQTRGSVPVFWSQVGYRY-NPRPRLDKSEKETSQYFALHFNQELGIYQKQVIIN 376

  Fly   310 LLGSSLVGSKEGEAMLSNEFQRHHGMSAHKDVPHVVFDYHQECRGGNFSALAKLKERIVACGANY 374
                 ||.....|.::.:.:.:...|..:.::.:|.||:|:.|||..|..:..|.:.|.....:.
 Frog   377 -----LVDQAGREKIIGDAYLKQVLMFNNPNLTYVTFDFHEHCRGMKFENVQTLTDAISDIIVDM 436

  Fly   375 GVFHASNGQVLREQFGVVRTNCLDCLDRTNCVQTYLGLDTLGIQLEALKMGGKQQNI-SRFEEIF 438
            .........|:.:|.|:.|.||:|||||||.||..:....:..||:.|.:...:|.: .:...::
 Frog   437 KWCWVDQAGVICKQEGIFRVNCMDCLDRTNVVQAAVARVIMEHQLKKLGVMPPEQPLPMKCYRLY 501

  Fly   439 RQMWINNGNEVSKIYAGTGAIQG-----GSK-----LMDGARSAARTIQNNLLDNSKQEAIDVLL 493
            :.||.|||:.:|:.||||.|::|     |.:     :.||..||.|...|...|..:|..|| |:
 Frog   502 QIMWANNGDSISRQYAGTAALKGDFTRTGERKLAGVMKDGVNSANRYYLNRFKDAYRQAVID-LM 565

  Fly   494 VGSTLSSELADRARILLPSNMLHAPT-----TVLRELCKRYTEYVRPRMARVAVGTYNVNGGKHF 553
            .|..::.:|............||..:     .::.:|.:.|.:.:.|       .....:||
 Frog   566 QGIPVTEDLYSIFTKEKEHEALHRESQRNHHELINQLLQNYMQMLLP-------DDEKFHGG--- 620

  Fly   554 RSIVFKDSLADW-LLDCHALARSKALVDVNNPSENVDHPVDIYAIGFEEIVDLNASNIMAASTDN 617
                       | |:||     ..:|:|..:      ..|::..:                 ..|
 Frog   621 -----------WALIDC-----DPSLIDATH------RDVEVLLL-----------------LSN 646

  Fly   618 AKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKTGLGGATGNKGAC 682
            ...:.......|.:.|.|..|:.:.|.    .|.|.|| ..........|::... ...||.|..
 Frog   647 CAYYVAYYDDEIDKVNQYQRLSLEDLE----RIEIGPE-PTFFGKPKFSCMRLHY-KYKGNSGYF 705

  Fly   683 -AIRFVLHG-------TSMCFVCAHFAAGQSQVAERNADYAEITRKLAFPMGRTLKSHDWVFWCG 739
             .:|.|...       |.:|.  |.......|..|  .|...|.:||.   .::.|.|:.:....
 Frog   706 HTLRAVTRNPDEDGKDTLLCI--AEMLRLTKQALE--LDVPVIEKKLE---RKSSKPHEEIIGIR 763

  Fly   740 DFNYRIDMEKDELKECVRNGDLSTVLEFDQLRKEQEAGNV--FGEF--LEGEITFDPTYKYDLFS 800
            ..:.|:.:....|.:. :|..:|.....:|..|:...|::  .|.|  .:|:....|..:.:::.
 Frog   764 SRSQRLGLNSMGLAQS-KNFLMSKFSSLNQKVKQTNIGSLRKLGGFNKPDGKGVLAPNLQANMWK 827

  Fly   801 DDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAASAWNPGKLIHYGRSELKQSDHRPVIAIIDAEI 865
            .|                              :|..|||       :::|
 Frog   828 SD------------------------------SSLDNPG-------TDIK--------------- 840

  Fly   866 MEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLESSATGDEDGPTIYDENVMSALITELSKMGEVTL 930
                               |.|:|.:.:.....|...|:......:|:..||  ..|..||:...
 Frog   841 -------------------GHPESDLDISTDSESFHSDDFLTKSDEEDGQSA--GALENMGQTDY 884

  Fly   931 VRYVEDTMWVTFRDGESALNASSKKSIQVCGLDLIL--------ELKSKDWQHLVDSEIEL--CT 985
            |                         :..||:.:.:        .:.|.|:.....:||.:  |.
 Frog   885 V-------------------------LPSCGIIVSVPRLGSRSHSVSSADFNPPNPTEIHVTECE 924

  Fly   986 TNTIPLCANPVEHAQLLQAITPELPQRPK-----QPPTRPPARPPMPMSPKNSPRHLPHVGVISI 1045
            ....|.....|:....:.|...:.....:     ..|....|:.....|..|||:
 Frog   925 EQDPPQTEALVDFGTPIDAYCHQFVHDAQTKGNLNEPDSKEAQLDQETSSNNSPK---------- 979

  Fly  1046 VPKPAKPPMPPQPQSQPLIPSPLQPQV-APPRPPAMDTTPSSKSQSPTELVSASSSTSSSGKTSP 1109
                              ||:||:... ..|||..:|.:.:|.:   ::|:
 Frog   980 ------------------IPAPLESDAELIPRPSQLDVSHNSAN---SQLL-------------- 1009

  Fly  1110 TAPAVLSGPPTPPRQMQSKQATPVSTPTRQVGSPKDPIPSDTAYETASNIYEEIQEDVPAPRHPP 1174
                    |..||:..:|.:|:|.|..|      ..|.|:|::...|.:.:.:|:..|....:..
 Frog  1010 --------PVEPPQLSKSGRASPASAST------SAPSPADSSSSRAVSPFAKIRSSVVQVANIT 1060

  Fly  1175 PAGPPPVIGAPMGPPPPLPNRRGPPPIPNRSGNAPPLPTRPANN 1218
            .||....|...:...     ::.|.|      ||||.|  |.|:
 Frog  1061 QAGLTQGINFAVAKV-----QKSPDP------NAPPEP--PQND 1091

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637	141/541 (26%)
		INPP5c_Synj	538..863	CDD:197323	53/337 (16%)
		DUF1866	862..1008	CDD:286093	22/155 (14%)
inpp5f	XP_031761377.1	COG5329	50..567	CDD:227637	142/540 (26%)
		hSac2	597..697	CDD:463592	23/154 (15%)