Protein Alignment Synj and inpp5jb

DIOPT Version :10

• Sequence 1: NP_569729.1
• Gene: Synj / 37517
• FlyBaseID: FBgn0034691
• Length: 1218
• Species: Drosophila melanogaster
• Sequence 2: XP_002662241.3
• Gene: inpp5jb / 100317089
• ZFINID: ZDB-GENE-081104-46
• Length: 657
• Species: Danio rerio
• Alignment Length: 637
• Identity: 161/637 - (25%)
• Similarity: 251/637 - (39%)
• Gaps: 151/637 - (23%)

  Fly   496 STLSSELADRARILLPSNMLHAPTT-----VLRELCKRYTEYVRPRMA---RVAVGTYNVNGGKH 552
            |...|.::.||..|..:.....|:|     ..|.|....|...:|::|   |:.:.|:||....
Zfish    96 SVARSHISMRAASLPQAPSYKPPSTESVVHPQRALSVAGTADTQPQVAEDFRIHIVTWNVGSAM- 159

  Fly   553 FRSIVFKDSLADWLLDCHALARSKALVDVNNPSENV---------DHPVDIYAIGFEEI---VDL 605
                                           |.|::         |...|:|.||.:|:   ::.
Zfish   160 -------------------------------PPEDITNLLGLNVGDGNTDMYIIGLQEVNSMINK 193

  Fly   606 NASNIMAASTDNAKLWAEELQKTISRDNDYVLLTYQQLVGVCLYIYIRPEHAPHIRDVAIDCVKT 670
            ...:::  .||.   |:|.....:| ...|||.|.|::.|:.|.::.:..|.|.:|.:.....:|
Zfish   194 RLKDVL--FTDQ---WSEVCMDALS-PFGYVLATSQRMQGMLLLVFAKYFHLPFLRGIQTQTTRT 252

  Fly   671 GLGGATGNKGACAIRFVLHGTSMCFVCAHFAAGQSQVAERNADYAEITRKLAFPMGRT---LKSH 732
            ||||..||||..:.|..:.|.|:||:..|..|......:|..|:..|.::..|. |:.   :..|
Zfish   253 GLGGIWGNKGGVSARMTVFGHSICFLNCHLPAHMENTEQRMEDFESILQQQQFD-GQAATGVLDH 316

  Fly   733 DWVFWCGDFNYRI-DMEKDELKECVRNGDLSTVLEFDQLRKEQEAGNVFGEFLEGEITFDPTYKY 796
            |.|||.||.|:|| |:|...:|..:.|..||.:.|.|||...:::..|...|.||.:.|.||||:
Zfish   317 DVVFWFGDLNFRIEDLEMQVVKGAIDNNKLSVLWEKDQLNIAKDSETVLEGFHEGPLKFPPTYKF 381

  Fly   797 DLFSDDYDTSEKQRAPAWTDRVLWRRRKALAEGDFAA-----SAWNPGKLI--HYGRSELKQ--S 852
            |:.:|.||||.|:|.||||||:|||.|......:..:     |....|..:  |:.||.::.  |
Zfish   382 DVGTDTYDTSGKKRMPAWTDRILWRLRPMAQVSNSTSKRSSLSGLTSGTRVSQHFYRSHMEYTVS 446

  Fly   853 DHRPVIAIIDAEI-MEIDQQRRRAVFEQVIRDLGPPDSTIVVHVLESSATGDEDGPTIYDENVMS 916
            ||:||.::...:. .::|........|...|::.  |:.....|..:.|....|...||
Zfish   447 DHKPVSSVFTLQFPYKVDMPLVTIFVEDEWREIS--DAVAKFKVAPNFARSSWDWIGIY------ 503

  Fly   917 ALITELSKMGEVTLVRYVEDTMWV-----TFRDGESALNASSKKSIQVCGLDLILELKSKDWQHL 976
                   |:|......||..| |.     .|...|..:|.:.::..:..| |.||...|.:...:
Zfish   504 -------KVGFKHHKDYVAYT-WAKQEESDFLRQEHQVNFTEEELPKESG-DFILGYYSNNTSSI 559

  Fly   977 V----------------------------DSEIELCTT-NTIPLCANPVEHAQLLQAITPELPQR 1012
            |                            |.|::...: ::.|...:||         :..|.:.
Zfish   560 VGITEPFQIQLPASAAAGLSPSDSSDFTSDDEVKKPDSGDSSPETEDPV---------SSRLTEE 615

  Fly  1013 PKQPPTRPPARPPMPMSPKNSPRHLPHVGVISIVP--------KPAKPPMPP 1056
            ....|:||.||          |||..|....::.|        |.|..|..|
Zfish   616 QMAKPSRPHAR----------PRHGKHHAGSAVQPSDEPENSGKAAAEPEEP 657

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Synj	NP_569729.1	COG5329	61..493	CDD:227637
		INPP5c_Synj	538..863	CDD:197323	106/352 (30%)
		DUF1866	862..1008	CDD:286093	29/180 (16%)
inpp5jb	XP_002662241.3	INPP5c_INPP5J-like	146..457	CDD:197328	105/349 (30%)
		SKICH	468..568	CDD:465482	23/116 (20%)