DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13501 and Rsph14

DIOPT Version :9

Sequence 1:	NP_611631.1	Gene:	CG13501 / 37510	FlyBaseID:	FBgn0034684	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	NP_001157005.1	Gene:	Rsph14 / 71236	MGIID:	1918486	Length:	374	Species:	Mus musculus

Alignment Length:	353	Identity:	75/353 - (21%)
Similarity:	126/353 - (35%)	Gaps:	116/353 - (32%)

- Green bases have known domain annotations that are detailed below.

  Fly    61 RAELAYGWFALPKLLKELDSDVRLTHWKAVVSLSEFVLNPLNAQRAIIEMDLVRKLKNAFM---- 121
            :|.:|||..||.||.:||.|...||..||:|:|.:.:.:|.....| |.:..:..||....
Mouse    51 KAAIAYGCRALSKLNEELQSRDLLTRQKALVALCDLMHDPEYVYEA-INIGCLESLKTLLQDDDN 114

  Fly   122 RMRLKHHKEEHREVEMYLRIYNILSRNLDGAENIANRKCLRVEFYKIIKNQEPIKDELASEILRN 186
            .:|:|           ...:..|::.:..|          ||.|.|             .:|:
Mouse   115 LVRIK-----------TTEVLYIMATHYVG----------RVGFLK-------------HDII-- 143

  Fly   187 LTCKPKVLGIFLEDPENFSALAEIFRQDPCRPQFPLH-LWHHLCDMLEVAPDRGI-ELGLFELLH 249
                 :.|.:.|.|           .|..||..  || .:.||..:.:.|  :|| :.||...|.
Mouse   144 -----QALSLLLSD-----------HQTLCREN--LHQAYKHLAQLPKGA--QGIVQSGLIPSLV 188

  Fly   250 SRILNRLSNFWDMNTKAFALLLCCAEGQRRFDAVDGVKLLYDVFAQPDENPRMLLPRQKVENWEY 314
            .::.....:..::.....|  ||..|     ||.:.:    :..|.|....::|....::.:...
Mouse   189 RKLQKEEDHIQEIILDTLA--LCLQE-----DATEAL----ESQAVPCLKEKLLSQNSEIRSKAA 242

  Fly   315 TAL-ALLNGLHSKRALWRSREFTQLPCYV---------------GRLM--TSTTD---------- 351
            .|| |:...|..|..:|:::   .:|..|               |.||  |.||:
Mouse   243 RALIAISIPLDGKNQVWKNK---VIPILVTLLSDTDEEVKANAAGALMHATVTTEGKYAALDANA 304

  Fly   352 ----------NPRLQIYCLKVFRELGVM 369
                      ||:.:: ||...:.|.::
Mouse   305 IEPLLELLSTNPKTKL-CLNATKALTML 331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13501	NP_611631.1	None
Rsph14	NP_001157005.1	HEAT repeat	102..126	CDD:293787	4/34 (12%)
		HEAT repeat	142..170	CDD:293787	11/47 (23%)
		ARM	176..286	CDD:237987	23/123 (19%)
		HEAT_2	184..287	CDD:290374	19/116 (16%)
		HEAT repeat	184..208	CDD:293787	2/25 (8%)
		armadillo repeat	223..248	CDD:293788	4/24 (17%)
		armadillo repeat	255..290	CDD:293788	7/37 (19%)
		ARM	257..370	CDD:237987	14/79 (18%)
		armadillo repeat	296..328	CDD:293788	4/32 (13%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15599
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	2	2.060