DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13501 and rsph14

DIOPT Version :9

Sequence 1:	NP_611631.1	Gene:	CG13501 / 37510	FlyBaseID:	FBgn0034684	Length:	413	Species:	Drosophila melanogaster
Sequence 2:	XP_002931962.2	Gene:	rsph14 / 594888	XenbaseID:	XB-GENE-980692	Length:	340	Species:	Xenopus tropicalis

Alignment Length:	398	Identity:	78/398 - (19%)
Similarity:	151/398 - (37%)	Gaps:	91/398 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    38 MEKRNICKCMPLCCNSTSTHLADRAELAYGWFALPKLLKELDSDVRLTHWKAVVSLSEFVLNPLN 102
            |.:..|..|:|...:.|      ::.:|:|..|||||.:||.....:|..:|:::|.:.|.:|.|
Frog     1 MAQARISCCLPPNIDPT------KSPVAFGERALPKLNEELKDSELITRQRALMALCDLVHDPEN 59

  Fly   103 AQRAIIEMDLVRKLKNAFMRMRLKHHKEEHREVEMYLRIYNILSRNLDGAENI-------ANRKC 160
            ..:| :.:..:..||:..       |.::....:....::.|::.:..|.:.|       |..|.
Frog    60 VYQA-VHLGFLESLKSLL-------HDQDSTVRQKATEVFYIMAGHSVGRQGILKSDVIPAISKL 116

  Fly   161 L-------RVEFYKIIK--NQEP------IKDELASEILRNLTCKPKVLGIFLEDPENFSALAEI 210
            |       |...:|..:  ::.|      :|..|..::::.|.|:       |||      :..|
Frog   117 LDDPVVICRQNMHKTFEMVSELPAGAAALVKANLVVQLVQKLECE-------LED------IQMI 168

  Fly   211 FRQDPCRPQFPLHLWHHLCDMLEVAPDRGIELGLFELLHSRILNRLSNFWDMNTKAFALLLCCAE 275
            ..:       .||.      ||:....:.:..|...:|..::.:..:....|..||...:....|
Frog   169 ILE-------TLHF------MLQTDVLQALSAGAVGILKGKLSHPSAGIRRMAAKALMDICVPLE 220

  Fly   276 GQRRFDAVDGVKLLYDVFAQPDENPRMLLPRQKVENWEYTALALLNGLHSKRALWRSREFTQLPC 340
            |:......:.|.||..:....|...|           ...|.||:|...:.:..:.:.....:|
Frog   221 GKETVCQEEVVPLLVHLLQDSDNEVR-----------ANAAGALMNITITTQGKYAAINSGAIP- 273

  Fly   341 YVGRLMTSTTDN-PRLQIYCLKVFRELGVMPCIKRYIIG--NWLQDICKLFCLDADAECARDA-- 400
               :|:...:|. .|:::..||....|...|..::.::.  |.:|.     |||..:|..|.|
Frog   274 ---KLLALVSDGYSRVRLNSLKALTTLSEAPEGRKVLLADVNIIQS-----CLDDQSEAVRRAAA 330

  Fly   401 ----LVDW 404
                ::.|
Frog   331 IAIQVIQW 338

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13501	NP_611631.1	None
rsph14	XP_002931962.2	SRP1	<27..>257	CDD:227396	54/274 (20%)
		HEAT repeat	27..55	CDD:293787	10/27 (37%)
		HEAT repeat	69..97	CDD:293787	4/34 (12%)
		HEAT repeat	109..140	CDD:293787	5/30 (17%)
		HEAT_2	197..294	CDD:379311	20/111 (18%)
		HEAT repeat	229..259	CDD:293787	9/40 (23%)
		HEAT repeat	269..296	CDD:293787	6/30 (20%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15599
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100