DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9308 and Tmed5

DIOPT Version :9

Sequence 1:	NP_611629.1	Gene:	CG9308 / 37507	FlyBaseID:	FBgn0034681	Length:	203	Species:	Drosophila melanogaster
Sequence 2:	NP_083152.1	Gene:	Tmed5 / 73130	MGIID:	1921586	Length:	229	Species:	Mus musculus

Alignment Length:	222	Identity:	57/222 - (25%)
Similarity:	109/222 - (49%)	Gaps:	30/222 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MLSAIVLVLVLFQAACGFIVTLDAHETM--------CFYDHANVSDKVTVSFEVMEGGFKDVGVE 57
            :|||  |...|.:.|.||..:||:..|.        |||....:...:.:.::|::||..|:...
Mouse    13 LLSA--LPAALLRGAAGFTPSLDSDFTFTLPAGRKECFYQPMPLKASLEIEYQVLDGGELDIDFH 75

  Fly    58 IAGPDDDRLHHSKQDTMGSFTFTAMKEGRYQLCFDNKMSTMTPKILMFQF---HVARAIEFYMDS 119
            :..|:...|...::.:.|..|... ::|.|..||||..||::.|::.|:.   ::...::...|.
Mouse    76 LTSPEGRTLVFEQRKSDGVHTIET-EDGDYMFCFDNTFSTISEKVIFFELILDNMGEEVQGQEDW 139

  Fly   120 SK----------RVDDVIEQATVQSMINQLSAKLGAVKMEQEYMHFRYRGHLEVSDMVELRVLAW 174
            .|          :::|::|  ::.|:.::|| |.|.::........|.| :::.|:..  ||..|
Mouse   140 KKYITNTDVLEMKLEDILE--SINSIKSRLS-KSGHIQTLLRAFEARDR-NIQESNFD--RVNFW 198

  Fly   175 SIFGPMMLIITAVLEVYYLKHFFEVKR 201
            |:...|::::.:.::||.||..||.||
Mouse   199 SVVNLMVMVVVSAIQVYTLKSLFEDKR 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9308	NP_611629.1	EMP24_GP25L	17..198	CDD:279450	47/201 (23%)
Tmed5	NP_083152.1	EMP24_GP25L	35..222	CDD:279450	43/193 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000272
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1510
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910