DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PEAR1 and CG17145

DIOPT Version :9

Sequence 1:XP_016856723.1 Gene:PEAR1 / 375033 HGNCID:33631 Length:1125 Species:Homo sapiens
Sequence 2:NP_001262098.1 Gene:CG17145 / 40215 FlyBaseID:FBgn0036953 Length:334 Species:Drosophila melanogaster


Alignment Length:346 Identity:76/346 - (21%)
Similarity:109/346 - (31%) Gaps:96/346 - (27%)


- Green bases have known domain annotations that are detailed below.


Human   384 GYTGDRCR--EECPVGRFGQDCAETCDCAPDARCFPANGACLCEHGF----TGDRCTDRLCPDGF 442
            |...|.||  ....|.|..:.|:::..|......:   ..|.....|    || :|...|...  
  Fly    24 GRNEDICRLFSNNTVIRDPESCSQSITCIDSVSYY---STCTGSTPFFDKDTG-KCVKSLSTS-- 82

Human   443 YGLSCQAPCTCDREHSLSCHPMNGECSCLPGWAGLHCNE-------SCPQDTHGPGCQEHCLCLH 500
             ..||...| .||.......|.    ||   :...:|.:       :|||:||.....:.|...|
  Fly    83 -TSSCSISC-ADRAKQFVADPK----SC---YGYYYCADEETALYGTCPQETHFNATTQMCSRQH 138

Human   501 GGVCQATSGLCQCAPGYTGPHCASLCPPDTYGVN------CSARCSCENAI----ACSPI----- 550
            ...|..:          |..:|:.:    ..|||      |:....||..:    .||..     
  Fly   139 ESDCTTS----------TFEYCSIV----KNGVNFDNLQGCNMYHVCEKGVLKDKTCSKTYYQAS 189

Human   551 DGECVCKEGWQRGNCSV-PCPPGTWG--------------FSCNASCQCAHEAVCSPQTGACTCT 600
            .||||.|   ...:|.. |.|....|              .:|.....||.:...:|..     .
  Fly   190 TGECVSK---ALVDCDAHPLPTDVCGKASKPYENKFVADEATCRGYFYCAKQKDGTPDP-----N 246

Human   601 PGWHGAHCQLPCPKGQFGEGCASRCDCDHSDGCDPVHGRCQCQ------AGWMGARCHLSCPEGL 659
            |.|:      .||:.:|.:..:..|....|..|.  |.||..:      :...|.|.:|||.:|:
  Fly   247 PVWN------QCPQDRFFDASSQMCITPSSVYCS--HDRCDGRTASFVVSATKGCRNYLSCSDGV 303

Human   660 W--GVNCSNTCTCKNGGTCLP 678
            .  ..:|.|.......|.|.|
  Fly   304 TVSERSCGNYFFDDQQGACTP 324

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
PEAR1XP_016856723.1 None
CG17145NP_001262098.1 CBM_14 91..142 CDD:279884 13/57 (23%)
CBM_14 278..327 CDD:279884 12/47 (26%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D561378at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
11.010

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