DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment PEAR1 and NimB1

DIOPT Version :9

Sequence 1:XP_016856723.1 Gene:PEAR1 / 375033 HGNCID:33631 Length:1125 Species:Homo sapiens
Sequence 2:NP_001260452.1 Gene:NimB1 / 34813 FlyBaseID:FBgn0027929 Length:403 Species:Drosophila melanogaster


Alignment Length:374 Identity:96/374 - (25%)
Similarity:118/374 - (31%) Gaps:150/374 - (40%)


- Green bases have known domain annotations that are detailed below.


Human   114 PAPSACSPQSPASGPGRAPILAPSPQTQRKLLASRDSFCM---VCVGVVYRTVYRQVVKTDHR-- 173
            |..:.|.|...||.|...                |:.||.   ||      ..:.:.|:.:|.  
  Fly    99 PYANECVPDCSASSPDNC----------------RNGFCRSPGVC------ECFAEFVRNEHGAC 141

Human   174 --------QRLQC-------CHGFY----ESRGFCVPLCAQEC-VHGRCVAPNQCQCVPGWRGD- 217
                    |..:|       ||..:    |:|.||.|.|:|.| .|..||||.||.|.||:|.. 
  Fly   142 IHTCPIACQHGRCYLNGTCVCHQNFVLDQETRQFCRPKCSQSCGTHEECVAPGQCDCSPGYRRTP 206

Human   218 --DCSSECAPGMWGPQCDKP--CSCGNNSSCDPKSGVCSCPSGLQPPNCLQPCTPGYYGPACQFR 278
              .|...|||.....:|..|  |.|.......|...||..       .|...|..|    .|:.|
  Fly   207 DLGCQPVCAPDCGFGKCVAPNQCECFAGFIKRPNWNVCEA-------ECYLNCENG----LCESR 260

Human   279 CQCH---GAPCDPQTGACFCPAERTGPSCDVSCSQGTSGFFCPSTHSCQNGGVFQTPQGSCSCPP 340
            .:||   |...|..|.:|.       |.|..:|.||             ||              
  Fly   261 YKCHCREGYRYDVNTTSCL-------PECSDNCGQG-------------NG-------------- 291

Human   341 GWMGTICSLPCPEGFHGPNCSQECRCHNGGLCDRFTGQCRCAPGYT--GDRCREECP---VGRFG 400
                 :|..|                          |.|||..||.  |..||.:|.   .|::|
  Fly   292 -----VCIAP--------------------------GVCRCFRGYEVHGAECRPKCESRFCGKYG 325

Human   401 QDCA-ETCDCAP-DARCFPANGA------CLCEHGFTG--DRC--TDRL 437
            :..| |.|.|.. ...|  .||:      |.|..|.|.  |||  .|||
  Fly   326 RCVAPEICGCGEGQQHC--RNGSCDDIEHCSCPSGETHFIDRCLKADRL 372



Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG1218
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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