Protein Alignment ppk9 and SCNN1G

DIOPT Version :9

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_001030.2
• Gene: SCNN1G / 6340
• HGNCID: 10602
• Length: 649
• Species: Homo sapiens
• Alignment Length: 574
• Identity: 99/574 - (17%)
• Similarity: 173/574 - (30%)
• Gaps: 222/574 - (38%)

  Fly   174 VERVLWLAFICVALFSIISLSKRTWHRFQTSPMVISMDRNKLVWNTSFPSLTVCPHKRIDELKVE 238
            :.|:||:.|...|:..|:.........|.|..:.|.:...||    .||::|:|        .:.
Human    51 LRRLLWIGFTLTAVALILWQCALLVFSFYTVSVSIKVHFRKL----DFPAVTIC--------NIN 103

  Fly   239 EYILAHPDQFLSEEDQEDFRDFIVKLASLTYDNLETLPLNKSYGIPST---KYLELLYELKWAFE 300
            .|..:.....|::.:||            |.:.|::|     ||.|.:   :..|....:....:
Human   104 PYKYSTVRHLLADLEQE------------TREALKSL-----YGFPESRKRREAESWNSVSEGKQ 151

  Fly   301 PEISSGAAVKMFIYETQTE-----------------------------------FGICHSVNSMV 330
            |..|.  .:.:.|::...:                                   |.:|.:..|..
Human   152 PRFSH--RIPLLIFDQDEKGKARDFFTGRKRKVGGSIIHKASNVMHIESKQVVGFQLCSNDTSDC 214

  Fly   331 ARY------NSFDYWRSGDW-------------SLMDHGDRVTV------------------HPL 358
            |.|      |:...|....:             ::....:.:.|                  ||:
Human   215 ATYTFSSGINAIQEWYKLHYMNIMAQVPLEKKINMSYSAEELLVTCFFDGVSCDARNFTLFHHPM 279

  Fly   359 DGEIYA------QIINLSTAYDVYFHGAGDVPSISKQRYT-------------FPESDYTTVELI 404
            .|..|.      :.| |||:.....:|...:..|:::.|.             ..:.:|..||.:
Human   280 HGNCYTFNNRENETI-LSTSMGGSEYGLQVILYINEEEYNPFLVSSTGAKVIIHRQDEYPFVEDV 343

  Fly   405 ALEIFTNEEARATK---------QRSCRFNYEAEEMMTVPI-------YSFGLCLSECRMFFALR 453
            ..||   |.|..|.         :.|..::...|:...|||       ||..:||..|.....:.
Human   344 GTEI---ETAMVTSIGMHLTESFKLSEPYSQCTEDGSDVPIRNIYNAAYSLQICLHSCFQTKMVE 405

  Fly   454 VCGCVPHFY-----RNRCGY----NHIFGTQMRNGRRLPVCGLEGIGCLVKIKREIISLKSDKYK 509
            .|||..:..     .|.|.|    |.::                   |..::.|..:       :
Human   406 KCGCAQYSQPLPPAANYCNYQQHPNWMY-------------------CYYQLHRAFV-------Q 444

  Fly   510 INCNCLANCDDSNFFVQSYRSRVWFLGANL-QWGILEHPKMQL---------------------- 551
            ....|.:.|.::..|      :.|.|..:| ||..:...|..|
Human   445 EELGCQSVCKEACSF------KEWTLTTSLAQWPSVVSEKWLLPVLTWDQGRQVNKKLNKTDLAK 503

  Fly   552 ---------RREVLFSFAD----VLVYIGGLVGFFLGCSALSFTEIIYYFTARF 592
                     :|.::.|.|:    :|...||.:|.::.||.:...|||..|...|
Human   504 LLIFYKDLNQRSIMESPANSIEMLLSNFGGQLGLWMSCSVVCVIEIIEVFFIDF 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	97/567 (17%)
SCNN1G	NP_001030.2	ENaC	24..630	CDD:273304	99/574 (17%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152194
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.750