Protein Alignment ppk9 and ASIC4

DIOPT Version :9

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_061144.4
• Gene: ASIC4 / 55515
• HGNCID: 21263
• Length: 539
• Species: Homo sapiens
• Alignment Length: 490
• Identity: 95/490 - (19%)
• Similarity: 169/490 - (34%)
• Gaps: 126/490 - (25%)

  Fly   154 FLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSIISLSKRTWHRFQTSPMVISMDRNKLVWN 218
            |...|::||.......|...:.|.||...:..:|.:.:..:......:.|.|.:::||.......
Human    45 FASTSTLHGLGRACGPGPHGLRRTLWALALLTSLAAFLYQAAGLARGYLTRPHLVAMDPAAPAPV 109

  Fly   219 TSFPSLTVCPHKRIDELKVEEYILAHPDQF--LSEEDQEDFRDFIVKLASLTYDNLETLP-LNKS 280
            ..||::|:|...|.....:.:..:.|....  |..:|::..|     .|.|.|...:.:. ||::
Human   110 AGFPAVTLCNINRFRHSALSDADIFHLANLTGLPPKDRDGHR-----AAGLRYPEPDMVDILNRT 169

  Fly   281 YGIPSTKYLELLYELKWAFEPEISSGAAVKMFIYETQTEFGICHSVN-----SMVARYNSF---- 336
                ..:..::|....::.....:|..:|   :|   |.:|.|::.|     |:.:|....
Human   170 ----GHQLADMLKSCNFSGHHCSASNFSV---VY---TRYGKCYTFNADPRSSLPSRAGGMGSGL 224

  Fly   337 ---------DY---WRSGDWSLMDHGDRVTVHPLDGEIYAQIINLSTAYDVYFH--GAGDVP--- 384
                     :|   ||..:.:..:.|.||.:|             |.....|.|  |.|..|
Human   225 EIMLDIQQEEYLPIWRETNETSFEAGIRVQIH-------------SQEEPPYIHQLGFGVSPGFQ 276

  Fly   385 ---SISKQRYTFPESDYTTVELIALEIFTNEEARATKQRSCRFNYEAE--EMMTVPIYSFGLCLS 444
               |..:||.|:....:                     .:||...|..  |:.....||...|..
Human   277 TFVSCQEQRLTYLPQPW---------------------GNCRAESELREPELQGYSAYSVSACRL 320

  Fly   445 ECRMFFALRVCG------------CVPHFYRNRCGYNHIFGTQMRNGRRLPV-----CGLEGIGC 492
            .|.....|:.|.            |.|:.| ..|. :|...: :..|...|.     |.|...|
Human   321 RCEKEAVLQRCHCRMVHMPGNETICPPNIY-IECA-DHTLDS-LGGGPEGPCFCPTPCNLTRYG- 381

  Fly   493 LVKIKREIISLKSDKYKINCNCLANCDDSNFFVQSY-RSRVW----FLGANLQWGILEHPKMQLR 552
                 :||..::          :.|...:.:..:.| |:..:    ||..::.:..|....|:.|
Human   382 -----KEISMVR----------IPNRGSARYLARKYNRNETYIRENFLVLDVFFEALTSEAMEQR 431

  Fly   553 REVLFSFADVLVYIGGLVGFFLGCSALSFTEIIYY 587
              ..:..:.:|..:||.:|.|:|.|.|:..||:.|
Human   432 --AAYGLSALLGDLGGQMGLFIGASILTLLEILDY 464

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	94/488 (19%)
ASIC4	NP_061144.4	ASC	40..488	CDD:413546	95/490 (19%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152200
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	4.850