Protein Alignment ppk9 and asic1b

DIOPT Version :10

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_999956.1
• Gene: asic1b / 407672
• ZFINID: ZDB-GENE-040513-1
• Length: 557
• Species: Danio rerio
• Alignment Length: 588
• Identity: 97/588 - (16%)
• Similarity: 187/588 - (31%)
• Gaps: 189/588 - (32%)

  Fly    80 STGSKTIAKANDGNAAINQPGPARSIRSFRRPPLWQPPPQD--HAQDGQEMEVLDRQKRKDCRPA 142
            ||..:.:.::..|           |.....:..:|....:.  :.::|.:.:..|..:.::....
Zfish    11 STDDEPVGRSRQG-----------SFDDHYKRVVWSKDGEQGKYQEEGDDPDAYDGPEDEEAPDI 64

  Fly   143 CLVKGQAFIIEFLQGSSIHG----FIYLAKLGLSFVERVLW-LAFICVALFSIISLSKRTWHRFQ 202
            .|.       .|..|.|:||    |:...|..   :.:.|| |.|:......::.:..|..:..|
Zfish    65 SLA-------TFFGGCSLHGANHVFVEDKKFS---IRQGLWALVFLLAISMFLLQVVDRVIYYLQ 119

  Fly   203 TSPMVISMDRNKLVWNTSFPSLTVCPHK--RIDELKVEEY-----ILAHPDQ------FLSEEDQ 254
            ...:.:..:||  ..|.:||::|:|.:.  |..:|...:.     :|.:.|.      ...|.|:
Zfish   120 YDYVTLLDERN--AKNMTFPAITLCNYNTFRRSQLSYSDLLFMGPLLGYEDNMAPGIPLAPEPDR 182

  Fly   255 EDFRDFIVKLASLTYDNLETLPLNKSYGIPSTKYLELLYELKWAFEPEISSGAAVKMFIYETQTE 319
            :..|..:.:..:.|...::                ::|.|..:|.:   ..||.....|:   |.
Zfish   183 QGSRFSLAEFFNRTRHRMD----------------DMLLECNFAGK---ECGAEHWREIF---TR 225

  Fly   320 FGICHSVNS--------------------MVARYNSFDY---WRSGDWSLMDHGDRVTVHPLDGE 361
            :|.|::.||                    ::......:|   |...|.:..:.|.:|.:|..|..
Zfish   226 YGKCYTFNSGQDGRPLLITTKGGMGNGLEIMLDIQQDEYLPVWGETDETTFEAGIKVQIHTQDEP 290

  Fly   362 IYAQIINLSTAYDVYFHGAGDVPSISKQRYTF---PESDYTTVELIALEIFTNEEARATKQRSCR 423
            .:...:....|     .|.....|..:||.|:   |..|                .:||...|..
Zfish   291 PFIDQLGFGVA-----PGFQTFVSCQEQRLTYLPPPWGD----------------CKATPIDSDF 334

  Fly   424 FNYEAEEMMTVPIYSFGLCLSECRMFFALRVCG------------CVPHFYRNRCGYNHIFGTQM 476
            ||          .||...|..:|...:.:..|.            |.|..|:.
Zfish   335 FN----------TYSITACRIDCETRYLVENCNCRMVHMPGDAPYCTPEQYKE------------ 377

  Fly   477 RNGRRLPVCGLEGIGCLVKIKREIISLKSDKYKINCNCLANCD-----------------DSNFF 524
                    |....:..||:        :.:.|   |.|...|:                 .:.:.
Zfish   378 --------CADPALDFLVE--------RDNDY---CVCETPCNMTRYGKELSFVRIPSKASAKYL 423

  Fly   525 VQSYRSRVWFLGANLQ-----WGILEHPKMQLRREVLFSFADVLVYIGGLVGFFLGCSALSFTEI 584
            .:.|.....::..|:.     :..|.:..::.::  .:..|.:|..|||.:|.|:|.|.|:..|:
Zfish   424 AKKYNKTEQYISDNIMVLDIFFEALNYETIEQKK--AYELAGLLGDIGGQMGLFIGASILTILEL 486

  Fly   585 IYY 587
            ..|
Zfish   487 FDY 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:459966	88/510 (17%)
asic1b	NP_999956.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	36..57		2/20 (10%)
		ENaC	66..548	CDD:273304	90/522 (17%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:Q1XA76	477..479		1/1 (100%)