Protein Alignment ppk9 and asic4b

DIOPT Version :10

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_999951.1
• Gene: asic4b / 407667
• ZFINID: ZDB-GENE-040513-6
• Length: 558
• Species: Danio rerio
• Alignment Length: 536
• Identity: 111/536 - (20%)
• Similarity: 179/536 - (33%)
• Gaps: 182/536 - (33%)

  Fly   129 EVLDRQKRKDCRPACLVKGQAFIIEFLQGSSIHGFIYLAK-LGLSFVERV-----LWLAFICVAL 187
            |.|.|||          :|.|.:..|...||:||   ||: ||.|  ||:     ||...:.|:|
Zfish    32 EGLRRQK----------EGMADLASFASSSSLHG---LARALGTS--ERLGFRQTLWGLALLVSL 81

  Fly   188 FSIISLSKRTWH--RFQTSPMVISMDRNKLVWNTSFPSLTVCPHKRIDELKVEEYILAHPDQFLS 250
            .  :.|.:.||.  .:...|.:.:: |.:.....:||::|:|...|.              :|.:
Zfish    82 G--LFLYQATWSAATYLERPHLAAL-REETRRELTFPAITLCNVNRF--------------RFSA 129

  Fly   251 EEDQEDFRDFIVKLASLTYDNLETLPLNKSYG-------IPSTKYLELLYELKWAFEPEISS--- 305
            ..|.:     |..||:||     .||.....|       .|....|::........|..:.|
Zfish   130 LTDAD-----IYHLANLT-----GLPPKSRKGHRPSELQYPPPNMLDIFQRTGHQLEDMLKSCNF 184

  Fly   306 ---GAAVKMF--IYETQTEFGICHSVN------------------SMVARYNSFDY---WRSGDW 344
               ..:.:.|  :|   |.:|.|::.|                  .|:......:|   ||..:.
Zfish   185 SGQNCSSEDFSVVY---TRYGKCYTFNGNKTSPKRVRQGGTGNGLEMMLDIQQDEYLPIWRETNE 246

  Fly   345 SLMDHGDRVTVHPLDGEIYAQIINLSTAYDVYFH--GAGDVP------SISKQRYTFPESDYTTV 401
            :.::.|.||.:|             |.....|.|  |.|..|      |..:||.|:....:
Zfish   247 TTLEAGIRVQIH-------------SQNEPPYIHQLGFGVSPGFQTFVSCQEQRLTYLPQPW--- 295

  Fly   402 ELIALEIFTNEEARATKQRSCRFNYEAEEMMTVP---IYSFGLCLSECRMFFALRVCGCVPHFYR 463
                              .:||.:.|.    .:|   .||...|...|......|.|
Zfish   296 ------------------GNCRASSEP----VIPGYDTYSVSACRLHCESTQVQREC-------- 330

  Fly   464 NRCGYNHIFGTQMRNGRRLPVCGLEGIGCLVKIKREIISLKSDKYKINCNCLANCDDSNFFVQ-- 526
             .|...|:.|.       ..:|....|.|:.|....:.....|    :|.|...|:.:.:..:
Zfish   331 -NCRMVHMPGD-------ADICAPSKIKCVDKALASLQKSTGD----SCPCETPCNLTRYGKELS 383

  Fly   527 ----------SYRSRVW----------FLGANLQWGILEHPKMQLRREVLFSFADVLVYIGGLVG 571
                      .|.||.:          ||..::.:..|.:..::.::  .:..|.:|..|||.:|
Zfish   384 MVKIPSRGSARYLSRKYQKSEEYIRDNFLILDIFFEALNYETIEQKK--AYDIAGLLGDIGGQMG 446

  Fly   572 FFLGCSALSFTEIIYY 587
            .|:|.|.|:..||:.|
Zfish   447 LFIGASILTILEILDY 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:459966	103/509 (20%)
asic4b	NP_999951.1	ENaC	54..497	CDD:273304	101/504 (20%)
		GAS motif, ion selectivity filter. /evidence=ECO:0000250|UniProtKB:P78348	450..452		1/1 (100%)