DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk9 and ppk12

DIOPT Version :9

Sequence 1:	NP_611622.2	Gene:	ppk9 / 37498	FlyBaseID:	FBgn0085398	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_611672.1	Gene:	ppk12 / 37566	FlyBaseID:	FBgn0034730	Length:	569	Species:	Drosophila melanogaster

Alignment Length:	525	Identity:	110/525 - (20%)
Similarity:	195/525 - (37%)	Gaps:	123/525 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   153 EFLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSIISLSKRTWHRFQTSPMVISMD-RNKLV 216
            :||..:|:||..::...|||..||..:|.....||...:.|....:.::.::|::|.:. :...:
  Fly    28 QFLNQTSLHGLKFVGDSGLSSWERSFFLGSFVTALIITVHLISNIYVKWDSTPVIIGISPQATSI 92

  Fly   217 WNTSFPSLTVCPHKRIDELKVEEY-----------ILAHPDQFLSEEDQEDFRDFIVKLASLTYD 270
            ....||::|:|...::....|..|           :|...|.:.|.|..|:|     ..::...:
  Fly    93 LKVPFPAITICNMNQVQRSLVANYREGSNESALLKLLCESDSWESSEADEEF-----SASNFVTN 152

  Fly   271 NLETLPLNKSYGIPSTKYLELLYELKWAFEPEISSGAAVKMFIYETQTEFGICHSVNSMVARY-- 333
            ||:......::.....:.  ||:....|.|...|      ....:..|:.|:|...|.....|
  Fly   153 NLKISEFVSNHSQSCERM--LLFCRFSAVERNCS------QLFQQILTDEGLCCVFNFQPPEYLY 209

  Fly   334 -----------NSFDYWRSGDWS---------------LMDHGDRVTV---HPLD---GEIYAQI 366
                       || |.:.|..|.               ....|..:|:   ..||   ||.|...
  Fly   210 KPFANNNRNLTNS-DGFESVMWDPESGYPEQLPPKFYPATASGTGITLGFTAVLDAEMGEYYCSS 273

  Fly   367 INLSTAYDVYFHGAGDVPSISKQRYTFPESDYTT---VELIALEIFTNEEARATKQRSCRFNYEA 428
            .| ...:.||||...:||.: |:........|.|   :|::..|......:.:...|.|.|..|
  Fly   274 TN-GPGFKVYFHNPIEVPKV-KEAGLISAIGYETNYRIEMVRAEAVPAIRSISRDGRQCLFKNE- 335

  Fly   429 EEMMTVPIYSFGLCLSECRMFFALRVCGCVPHFYRNRCGYNH--IFGTQMRNGRRLPVCGLEGIG 491
            :|::...||:...|.:||...|....|.|:|        ::|  |:.       ...:|.:....
  Fly   336 KELIFYRIYTRLNCENECLAAFLYDTCSCIP--------FDHPLIYS-------NASICSMGDTS 385

  Fly   492 CLVKIKREIISLKSDKYKINCNCLANCDDSNF-----------------------FVQSYRSR-- 531
            |:.:.:|  .|.:....|....||.:|.|.|:                       |.:||.|:
  Fly   386 CVRRAQR--ASNRPGWAKCRQQCLPSCFDLNYLASGFSFPLASNNFQLANALVESFNKSYLSKNI 448

  Fly   532 ----VWFLGANLQWGILEHPKMQLRREVLFSFADVLVYIGGLVGFFLGCSALSFTEIIYYFTARF 592
                |:| ..::.:|..::..:.|        .:.|..:||::|.|:|.|.:|..||:|:...:.
  Fly   449 AVINVYF-RESVYYGNTKNAYVGL--------TEFLSNVGGVMGLFMGFSVISLAEILYFLILKP 504

  Fly   593 VRRMF 597
            :..:|
  Fly   505 LAELF 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	108/512 (21%)
ppk12	NP_611672.1	deg-1	28..499	CDD:273309	108/513 (21%)
ppk12	NP_611672.1	ASC	29..499	CDD:279230	108/512 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45456746
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.850