DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk9 and ppk7

DIOPT Version :9

Sequence 1:	NP_611622.2	Gene:	ppk9 / 37498	FlyBaseID:	FBgn0085398	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_609016.2	Gene:	ppk7 / 33886	FlyBaseID:	FBgn0031802	Length:	573	Species:	Drosophila melanogaster

Alignment Length:	535	Identity:	116/535 - (21%)
Similarity:	201/535 - (37%)	Gaps:	133/535 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly   133 RQKRKDCRPACLVKGQA-----FIIEFLQGSSIHGFIYLAKLGLSFVERVLWL-----AFICVAL 187
            :|:::..|.:.|.:..|     ..:.|.:.::|||...|.....|..||.:||     ||:....
  Fly    12 QQQQQPSRSSRLAQQLAQSSWQLALRFGKRTTIHGLDRLLSAKASRWERFVWLCTFVSAFLGAVY 76

  Fly   188 FSIISLSKRTWHRFQTSPMVISMDRNKLVWNTSFPSLTVCPHKRIDELKVEEYILAHPDQFL--- 249
            ..:|..::.....|||   |:...|.. |:...||.:|:|...|::..::.|    ...:||
  Fly    77 VCLILSARYNAAHFQT---VVDSTRFP-VYRIPFPVITICNRNRLNWQRLAE----AKSRFLANG 133

  Fly   250 SEEDQEDFRDFIVKLASLTYDN-------------------LETLPLNKSYGIPSTKYLELLYEL 295
            |...|::..:.||.    |||:                   |..:..::.....:.:..|||.|.
  Fly   134 SNSAQQELFELIVG----TYDDAYFGHFQSFERLRNQPTELLNYVNFSQVVDFMTWRCNELLAEC 194

  Fly   296 KWAFEP----EISSGAAVKMFIYETQTEFGICHSVNSMVA----RYNSFD---YWRSGDWSLMDH 349
            .|....    ||.|         :.:::.|:|.:.||:..    |....|   .||:|....|..
  Fly   195 LWRHHAYDCCEIFS---------KRRSKNGLCWAFNSLETEEGRRMQLLDPMWPWRTGSAGPMSA 250

  Fly   350 -GDRVTVHPLDGEIYAQIINLSTAYDV------YFHGAGDVPSISKQRYTFPESDYTTVELIALE 407
             ..||.:.|.......:..|.....||      .:|         ...:....:..||:|:..:.
  Fly   251 LSVRVLIQPAKHWPGHRETNAMKGIDVMVTEPFVWH---------NNPFFVAANTETTMEIEPVI 306

  Fly   408 IFTNEEARATK--QRSCRFN--YEAEEMMTVP--IYSFGLCLSECRMFFALRVCGCV------PH 460
            .|.:.:.|..:  ||.|.|:  :.:::..::.  :|....|.|||...:.:|.|.|.      |.
  Fly   307 YFYDNDTRGVRSDQRQCVFDDEHNSKDFKSLQGYVYMIENCQSECHQEYLVRYCNCTMDLLFPPG 371

  Fly   461 FYRNRCGYNHIFGTQMRNGRRLPVCGLEGIGCLVKIKREII---------SLKSDKYKINCNCLA 516
            .||:                    |..:.:.||.:....:|         .:::....::|.|..
  Fly   372 QYRS--------------------CRAQDLLCLAEHNDLLIYSHNPGEKEFVRNQFQGMSCKCFR 416

  Fly   517 NCDDSNFFVQSYRSRVWFLG----ANLQWGILE-HPK----MQLRREVLFSFADVLVYIGGLVGF 572
            ||...|:...   .|..||.    ||..:..|: |.:    |..|..::|.:.|::|..||:.|.
  Fly   417 NCYSLNYISD---VRPAFLPPDVYANNSYVDLDVHFRFETIMVYRTSLVFGWVDLMVSFGGIAGL 478

  Fly   573 FLGCSALSFTEIIYY 587
            |||||.:|..|:.|:
  Fly   479 FLGCSLISGMELAYF 493

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	111/507 (22%)
ppk7	NP_609016.2	ASC	38..493	CDD:279230	111/507 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.920