DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment ppk9 and ppk13

DIOPT Version :9

Sequence 1:	NP_611622.2	Gene:	ppk9 / 37498	FlyBaseID:	FBgn0085398	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	NP_001014495.1	Gene:	ppk13 / 3346226	FlyBaseID:	FBgn0053508	Length:	460	Species:	Drosophila melanogaster

Alignment Length:	492	Identity:	120/492 - (24%)
Similarity:	206/492 - (41%)	Gaps:	111/492 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 IIEFLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSIISLSKRTWHRFQTSPMVISMDRNKL 215
            |.|:|:.|::||..::.....|::||:.|:..:..:.::...|.|.:...|:.:.:...::.:..
  Fly     7 IEEYLKNSTLHGARFIVDKDASWIERIFWVICLVASWYASWLLIKASLSAFENNAISFVVESSFR 71

  Fly   216 VWNTSFPSLTVCPHKRIDEL-KVEEYILAHPDQFLSEEDQEDFRDFIVK-------------LAS 266
            .|||:||::.||..|.:|.: :|.|.:......|..||...:...|..:             .||
  Fly    72 DWNTNFPAIIVCESKNMDRIQEVAEQLWGADHDFTLEEVLSEIAFFRGESYHTVHECSGEEVTAS 136

  Fly   267 LTYDNLETLPLNKSYGIPSTKYLEL--------LYELKWAFEP-EISSGAAVKMFIYETQTEFGI 322
            ..|.|.       ||      |.||        :...:|..:| |...      :.:..:||.||
  Fly   137 CFYSNF-------SY------YAELVRSSCVDSISNCEWNNKPFECCK------YFHRMETELGI 182

  Fly   323 CHSVNSMVA------RYNSFDYWRSGDWSLMDHGDRVTVHPLDGEIYAQIINLSTAYDVYFHGAG 381
            |:::|||.|      :.|.:....||..:|.                   :.|.|...|:..|..
  Fly   183 CYAINSMQAGKPKMPKLNMYSNRGSGPGALK-------------------MELHTEATVFILGTE 228

  Fly   382 DVPSISKQRYTFPESDYTTV--------ELIALEIFTNEEARATK--QRSCRFNYEAEEMMTV-P 435
            :||::     ..|::|:..|        .:...:|..:||.|.|.  ||:|||  ..|.::.| .
  Fly   229 EVPTL-----VTPKTDFLVVGPYISFVRYISKRDIENDEEIRQTSVHQRNCRF--ADENILDVHK 286

  Fly   436 IYSFGLCLSECRMFFALRVCGCVPHFYRNRCGYNHIFGTQMRNGRRLPVCGLEGIGCLVKIKRE- 499
            .||:..|..:||....:.:|.|..|...|...:.              :|.:||:.||.:...:
  Fly   287 FYSYSACTVQCRKDRQMELCNCSSHLSPNSPDWQ--------------LCNMEGLECLNRNYEDL 337

  Fly   500 -IISLKSDKYK----INCNCLANCDDSNFFVQSYRSRVWFLG-----ANLQWGILEHPKMQLRRE 554
             :|..|..|.:    :.|:||.:|.:.: ....|.|:....|     :.::.|::|.|..:.:|.
  Fly   338 SVIIAKWSKLRGRKGLVCDCLPSCTEVD-ITTVYDSKENMAGSQNAISRIEVGLIELPTERYKRN 401

  Fly   555 VLFSFADVLVYIGGLVGFFLGCSALSFTEIIYYFTAR 591
            ::....|::|.|||..|.|:|.|.|||.||.||.|.|
  Fly   402 LVRGKLDLVVSIGGTTGLFVGASLLSFVEIFYYITIR 438

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	114/483 (24%)
ppk13	NP_001014495.1	ASC	10..434	CDD:279230	114/483 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	56	1.000	Domainoid score	I7319
eggNOG	1	0.900	-	-		E1_KOG4294
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11690
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	5	4.920