DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ppk9 and Asic3

DIOPT Version :9

Sequence 1:	NP_611622.2	Gene:	ppk9 / 37498	FlyBaseID:	FBgn0085398	Length:	599	Species:	Drosophila melanogaster
Sequence 2:	XP_038963092.1	Gene:	Asic3 / 286920	RGDID:	708578	Length:	564	Species:	Rattus norvegicus

Alignment Length:	557	Identity:	97/557 - (17%)
Similarity:	172/557 - (30%)	Gaps:	199/557 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   128 MEVLDRQKRKDCRPACLVKGQAFIIEFLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSI-- 190
            :|...|::..|.|            .|....::||..::...|...:.|.||...:.::|.:.
  Rat     7 LEEAQRRQASDIR------------VFASSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLY 59

  Fly   191 -ISLSKRTWHRFQTSPMVISMDRNKLVWNTSFPSLTVC---PHKR-----------------IDE 234
             ::...|.:..|.....:...:.::|    :||::|:|   |.:|                 :|.
  Rat    60 QVAERVRYYGEFHHKTTLDERESHQL----TFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDP 120

  Fly   235 LKVEEYILA-----HPDQFLSEEDQEDFRDFIVKLASLTYDNLETLPLNKSYGIPSTKYLELLYE 294
            .:...|:.|     .|..|               :.|.|:|      :.:.|........::|.:
  Rat   121 AEHAAYLRALGQPPAPPGF---------------MPSPTFD------MAQLYARAGHSLEDMLLD 164

  Fly   295 LKWAFEPEISSGAAVKMFIYETQTEFGICHSVNS-----------------------MVARYNSF 336
            .::..:|   .|......|:   |..|.|::.||                       .|.:....
  Rat   165 CRYRGQP---CGPENFTVIF---TRMGQCYTFNSGAHGAELLTTPKGGAGNGLEIMLDVQQEEYL 223

  Fly   337 DYWRSGDWSLMDHGDRVTVHPLDGEIYAQIINLSTAYDVYFHGAGDVP------SISKQRYTF-- 393
            ..|:..:.:..:.|.||.:|..|.         ..|.|..  |.|..|      |..:|:.:|
  Rat   224 PIWKDMEETPFEVGIRVQIHSQDE---------PPAIDQL--GFGAAPGHQTFVSCQQQQLSFLP 277

  Fly   394 -PESDYTTVELIALEIFTNEEARATKQRSCRFNYEAEEMM------TVPIYSFGLCLSECRMFFA 451
             |..|..|..|...:                |:.|..:.:      ..|.||...|...|...:.
  Rat   278 PPWGDCNTASLDPDD----------------FDPEPSDPLGSPRPRPSPPYSLIGCRLACESRYV 326

  Fly   452 LRVCGCVPHFYRNRCGYNHIFGTQMRNGRRLPVCGLEGIGCLVKIKREIISLKSDKY--KINCNC 514
            .|.||         |...|:.|..       |||..:..       ::..|...|..  |..|.|
  Rat   327 ARKCG---------CRMMHMPGNS-------PVCSPQQY-------KDCASPALDAMLRKDTCVC 368

  Fly   515 LANC-----------------DDSNFFVQSY-RSR-----------VWFLGANLQWGILEHPKMQ 550
            ...|                 ..:.:..:.| ||.           ::|...|.:         .
  Rat   369 PNPCATTRYAKELSMVRIPSRASARYLARKYNRSESYITENVLVLDIFFEALNYE---------A 424

  Fly   551 LRREVLFSFADVLVYIGGLVGFFLGCSALSFTEIIYY 587
            :.::..:..:::|..|||.:|.|:|.|.|:..||:.|
  Rat   425 VEQKAAYEVSELLGDIGGQMGLFIGASLLTILEILDY 461

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:279230	92/529 (17%)
Asic3	XP_038963092.1	ASC	17..547	CDD:413546	95/547 (17%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166345681
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4294
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D303969at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11690
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.850