Protein Alignment ppk9 and Asic2

DIOPT Version :10

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_037024.2
• Gene: Asic2 / 25364
• RGDID: 2017
• Length: 563
• Species: Rattus norvegicus
• Alignment Length: 614
• Identity: 118/614 - (19%)
• Similarity: 196/614 - (31%)
• Gaps: 219/614 - (35%)

  Fly    80 STGSKTIAKANDG----NAAINQPGPARSIRSFRRP-------PLWQPPPQDHAQDGQEMEVLDR 133
            |.|::..|.|..|    ..|..||.|. ::.:.|:|       |..|.|  ..|:.|
  Rat     4 SGGARLPATALSGPGRFRMAREQPAPV-AVAAARQPGGDRSGDPALQGP--GVARRG-------- 57

  Fly   134 QKRKDCRPACLVKGQAFIIEFLQGSSIHGFIYL----AKLGLSFVERVLWLAFICVALFSIISLS 194
                  ||:            |..:.:||..::    ...|.||..|.||:...|.:|..::|.|
  Rat    58 ------RPS------------LSRTKLHGLRHMCAGRTAAGGSFQRRALWVLAFCTSLGLLLSWS 104

  Fly   195 KRT---WHRFQTSPMVISMDRNKLVWNTS--FPSLTVCPHK--RIDEL-KVEEYILAH------P 245
            ...   |..|.      |..|....|:..  ||::|||.:.  |...| |.:.|...|      |
  Rat   105 SNRLLYWLSFP------SHTRVHREWSRQLPFPAVTVCNNNPLRFPRLSKGDLYYAGHWLGLLLP 163

  Fly   246 DQ----FLSE--EDQEDFRDFIVKLASLTYDNLETLPLNKSYGIPSTKYLELLYELKWAFEPEIS 304
            ::    .:||  ...|..|.:..|||    |....||.....|| |..:::.|
  Rat   164 NRTARPLVSELLRGDEPRRQWFRKLA----DFRLFLPPRHFEGI-SAAFMDRL------------ 211

  Fly   305 SGAAVKMFIYETQTEFGIC--HSVNSMVARYNSFDYWRSGDWSLMDHGDRVTVHPLDGEIYAQII 367
             |..::..:...:....:|  |:.:|:..:|.....:.||:               ||:.....:
  Rat   212 -GHQLEDMLLSCKYRGELCGPHNFSSVFTKYGKCYMFNSGE---------------DGKPLLTTV 260

  Fly   368 NLSTAYDVYFHGAGDVPSISKQRY--TFPESDYTTVEL-IALEIFTNEEAR-------------- 415
            ...|.     :|...:..|.:..|  .:.|::.||.|. :.::|.:..|..
  Rat   261 KGGTG-----NGLEIMLDIQQDEYLPIWGETEETTFEAGVKVQIHSQSEPPFIQELGFGVAPGFQ 320

  Fly   416 ---ATKQRSCRFNY--------EAEEMMT--VPIYSFGLCLSECRMFFALRVCG----------- 456
               ||:::  |..|        .:.||..  .|:||...|..:|...:.:..|.
  Rat   321 TFVATQEQ--RLTYLPPPWGECRSSEMGLDFFPVYSITACRIDCETRYIVENCNCRMVHMPGDAP 383

  Fly   457 -CVPHFYRNRCGYNHIFGTQMRNGRRLPVCGLEGIGCLVKIKREIISLKSDKYKINCNCLANCD- 519
             |.|..::.                    |....:|.|.:        |...|   |.|...|:
  Rat   384 FCTPEQHKE--------------------CAEPALGLLAE--------KDSNY---CLCRTPCNL 417

  Fly   520 ----------------DSNFFVQSYRSRVWFLGAN----------LQWGILEHPKMQLRREVLFS 558
                            .:.:..:.:.....::..|          |.:..:|..|       .:.
  Rat   418 TRYNKELSMVKIPSKTSAKYLEKKFNKSEKYISENILVLDIFFEALNYETIEQKK-------AYE 475

  Fly   559 FADVLVYIGGLVGFFLGCSALSFTEIIYY 587
            .|.:|..|||.:|.|:|.|.|:..|:..|
  Rat   476 VAALLGDIGGQMGLFIGASLLTILELFDY 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:459966	99/527 (19%)
Asic2	NP_037024.2	ENaC	64..557	CDD:273304	99/525 (19%)