Protein Alignment ppk9 and Scnn1a

DIOPT Version :10

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: NP_113736.1
• Gene: Scnn1a / 25122
• RGDID: 3639
• Length: 699
• Species: Rattus norvegicus
• Alignment Length: 653
• Identity: 119/653 - (18%)
• Similarity: 210/653 - (32%)
• Gaps: 216/653 - (33%)

  Fly    75 HNPNGSTGSKTIAKANDGNAAINQ-PGPARSIRSF-----RRPPLWQPPPQDHAQDGQEMEVL-- 131
            |..|...||.      .||....| |.|.:.::..     |......|.|....|..:|.|.|
  Rat    18 HASNSPKGSM------KGNQFKEQDPCPPQPMQGLGKGDKREEQGLGPEPSAPRQPTEEEEALIE 76

  Fly   132 -DRQKRKDCRPACLVKGQAFIIEFL-QGSSIHGFIYLA-----KLGLSFVERVLWLAFICVALFS 189
             .|..|:             :.:|. ..::|||.|.|.     ::..:| ..||||....:..:.
  Rat    77 FHRSYRE-------------LFQFFCNNTTIHGAIRLVCSKHNRMKTAF-WAVLWLCTFGMMYWQ 127

  Fly   190 IISLSKRTWHRFQTSPMVISMDRN--KLVWNTSFPSLTVC---PHK------RIDEL-KVEEYIL 242
            ...|    :..:.:.|:.::::.|  |||    ||::|||   |::      .::|| ::.|..|
  Rat   128 FALL----FEEYLSYPVSLNINLNSDKLV----FPAVTVCTLNPYRYTEIKEELEELDRITEQTL 184

  Fly   243 ----------------------------AHPDQFL--------------------SEEDQEDFRD 259
                                        .||.|.|                    ....|.|.:|
  Rat   185 FDLYKYNSSYTRQAGARRRSSRDLLGAFPHPLQRLRTPPPPYSGRTARSGSSSVRDNNPQVDRKD 249

  Fly   260 FIVKLASLTYDNLETLPLNKSYGIPSTK------YLELLYEL---KWAFEPEISSGAAVKMFIYE 315
            :.:.......:..:......|.|:.:.:      |:.:|..|   ..|.|.|     |:..||:.
  Rat   250 WKIGFQLCNQNKSDCFYQTYSSGVDAVREWYRFHYINILSRLSDTSPALEEE-----ALGNFIFT 309

  Fly   316 TQTE----------------FGICHSVNSMVARYNSFDYWRSGDWSL--MDHGDRVTVHPLDGEI 362
            .:..                :|.|::.|..    |:.:.|.|   |:  :::|..:|:.....:
  Rat   310 CRFNQAPCNQANYSKFHHPMYGNCYTFNDK----NNSNLWMS---SMPGVNNGLSLTLRTEQND- 366

  Fly   363 YAQIINLSTAYDVYFHGAGDVPSISKQRYTFPESDYTTVELIALEIFTNEEARATKQRSCRFNYE 427
            :..:::..|...|..||..:...:....:.......|::.:           |.....|...||.
  Rat   367 FIPLLSTVTGARVMVHGQDEPAFMDDGGFNLRPGVETSISM-----------RKEALDSLGGNYG 420

  Fly   428 --AEEMMTVPI-------YSFGLCLSECRMFFALRVCGCVPHFYRNR-----CGYNHIFGTQMRN 478
              .|....||:       |:..:|:..|.....::.|||...||...     |.|        |.
  Rat   421 DCTENGSDVPVKNLYPSKYTQQVCIHSCFQENMIKKCGCAYIFYPKPKGVEFCDY--------RK 477

  Fly   479 GRRLPVC--------GLEGIGCLVKIKR--EII------------SLKSDKYKINCNCLANCDDS 521
            ......|        .|:.:||..|.::  .:|            |:||..:......|.|
  Rat   478 QSSWGYCYYKLQGAFSLDSLGCFSKCRKPCSVINYKLSAGYSRWPSVKSQDWIFEMLSLQN---- 538

  Fly   522 NFFVQSYRS-----RVWFLGANLQWGILEHPKMQLRREVLFSFADVLVYIGGLVGFFLGCSALSF 581
            |:.:.:.|:     .::|...|.:.. .|.|.:        :...:|..:|.....:.|.|.||.
  Rat   539 NYTINNKRNGVAKLNIFFKELNYKTN-SESPSV--------TMVSLLSNLGSQWSLWFGSSVLSV 594

  Fly   582 TEI 584
            .|:
  Rat   595 VEM 597

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:459966	101/565 (18%)
Scnn1a	NP_113736.1	ENaC	80..677	CDD:273304	102/585 (17%)