Protein Alignment ppk9 and Asic3

DIOPT Version :10

• Sequence 1: NP_611622.2
• Gene: ppk9 / 37498
• FlyBaseID: FBgn0085398
• Length: 599
• Species: Drosophila melanogaster
• Sequence 2: XP_006535700.1
• Gene: Asic3 / 171209
• MGIID: 2159339
• Length: 563
• Species: Mus musculus
• Alignment Length: 580
• Identity: 101/580 - (17%)
• Similarity: 187/580 - (32%)
• Gaps: 197/580 - (33%)

  Fly   128 MEVLDRQKRKDCRPACLVKGQAFIIEFLQGSSIHGFIYLAKLGLSFVERVLWLAFICVALFSI-- 190
            :|...|::..|.|            .|....::||..::...|...:.|.||...:.::|.:.
Mouse     7 LEEAQRRQASDIR------------VFANSCTMHGLGHIFGPGGLTLRRGLWATAVLLSLAAFLY 59

  Fly   191 -ISLSKRTWHRFQTSPMVISMDRNKLVWNTSFPSLTVC---PHKR-----------------IDE 234
             ::...|.:..|.....:...:.::|    :||::|:|   |.:|                 :|.
Mouse    60 QVAERVRYYGEFHHKTTLDERESHQL----TFPAVTLCNINPLRRSRLTPNDLHWAGTALLGLDP 120

  Fly   235 LKVEEYILA-----HPDQFLSEEDQEDFRDFIVKLASLTYDNLETLPLNKSYGIPSTKYLELLYE 294
            .:...|:.|     .|..|               :.|.|:|      :.:.|........::|.:
Mouse   121 AEHAAYLRALGQPPAPPGF---------------MPSPTFD------MAQLYARAGHSLEDMLLD 164

  Fly   295 LKWAFEPEISSGAAVKMFIYETQTEFGICHSVNS-----------------------MVARYNSF 336
            .::..:|   .|......|:   |..|.|::.||                       .|.:....
Mouse   165 CRYRGQP---CGPENFTVIF---TRMGQCYTFNSGAQGAELLTTPKGGAGNGLEIMLDVQQEEYL 223

  Fly   337 DYWRSGDWSLMDHGDRVTVHPLDGEIYAQIINLSTAYDVYFHGAGDVP------SISKQRYTF-- 393
            ..|:..:.:..:.|.||.:|   |:.....|:..        |.|..|      |..:|:.:|
Mouse   224 PIWKDMEETPFEVGIRVQIH---GQEEPPAIDQL--------GFGAAPGHQTFVSCQQQQLSFLP 277

  Fly   394 -PESDYTTVELIALEIFTNEEARATKQRSCRFNYEAEEMM----TVPIYSFGLCLSECRMFFALR 453
             |..|..|..:                 ...|:.|..:.:    :.|.||...|...|...:..|
Mouse   278 PPWGDCNTASV-----------------DPDFDPEPSDPLGSPSSSPPYSLIGCRLACESRYVAR 325

  Fly   454 VCG------------CVPHFYRNRC-----GYNHIFGTQMRNGRRLPV--------CGLEGIGCL 493
            .||            |.|..|:: |     |..|:|.        |||        ..|..:...
Mouse   326 KCGCRMMHMPGNSPVCSPQQYKD-CASPALGKAHLFS--------LPVPIHSDIDHNPLGQVLLF 381

  Fly   494 VKIKREIISLKSDKYKINCNCLANC-----------------DDSNFFVQSY-RSRVWF----LG 536
            :.::.....|:.|    .|.|...|                 ..:.:..:.| ||..:.    |.
Mouse   382 LALRPADAMLRKD----TCVCPNPCATTRYAKELSMVRIPSRASARYLARKYNRSETYITENVLV 442

  Fly   537 ANLQWGILEHPKMQLRREVLFSFADVLVYIGGLVGFFLGCSALSFTEIIYYFTARFVRRM 596
            .::.:..|.:..::  ::..:..:::|..|||.:|.|:|.|.|:..||:.|....|..|:
Mouse   443 LDIFFEALNYEAVE--QKAAYEVSELLGDIGGQMGLFIGASLLTILEILDYLCEVFQDRV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ppk9	NP_611622.2	ASC	154..587	CDD:459966	94/543 (17%)
Asic3	XP_006535700.1	ENaC	21..546	CDD:273304	97/554 (18%)