DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpN58A and PPQ1

DIOPT Version :9

Sequence 1:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_015146.1	Gene:	PPQ1 / 855923	SGDID:	S000006100	Length:	549	Species:	Saccharomyces cerevisiae

Alignment Length:	310	Identity:	159/310 - (51%)
Similarity:	220/310 - (70%)	Gaps:	9/310 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 DEGINLDQIIAKLKLIGEIGSVVQISVR--------EIEAVCSRAREVLLKQPTLLEIPAPINLL 75
            :||:::|..|.||..:||...:.:.|.:        ||:.:|..|||:.|.|||||.:.|||.::
Yeast   235 NEGLDIDVAIEKLLQVGESREITKTSKKKNFPFHSWEIQLICYHAREIFLNQPTLLRLQAPIKVV 299

  Fly    76 GDIHGQYLNLLRYFESNGYPPDSVYLLLGDYVDRGKQSIETLTLLLALKARYPTKFYLLRGNHEC 140
            ||:|||:.:|||..:.:|.|.|:.||.|||||||||.|:||:.|||..|.:|...|::||||||.
Yeast   300 GDVHGQFNDLLRILKLSGVPSDTNYLFLGDYVDRGKNSLETILLLLCYKIKYKDNFFMLRGNHES 364

  Fly   141 SSINHFYGFYDECKRRYTVKLWRTFVDCYNCLPLAAIIEENIFCCHGGLSPHLFSMQQIREIRRP 205
            :::...||||||||||.:.|:|:.|||.:|.|||||||::.|||.|||:||.|..|:||.::.||
Yeast   365 ANVTKMYGFYDECKRRLSSKVWKMFVDVFNTLPLAAIIQDKIFCVHGGISPDLHDMKQIEKVARP 429

  Fly   206 IEIPESGLICDILWSDPDLRIMGWGPNERGVSHTFGSDVVSAFLHRFKLNLICRGHQVVEDGYEF 270
            .:||||||:.|:||||||.::..|..|:||||:||....|..|..:||.:||.|||.||||||||
Yeast   430 TDIPESGLVTDLLWSDPDPQVTDWSENDRGVSYTFSKRNVLDFCAKFKFDLILRGHMVVEDGYEF 494

  Fly   271 FAKRQLITIFSAPNYCGEFDNAGAMMCINQDLLCTFRVQRP-ILSEQRRL 319
            ||:::.:||||||||||||.|.||:|.:...::|:|.:.:| .|..:::|
Yeast   495 FARKKFVTIFSAPNYCGEFHNWGAVMSVTTGMMCSFELLKPRALKNKKKL 544

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	154/296 (52%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	154/295 (52%)
PPQ1	NP_015146.1	MPP_PP1_PPKL	239..535	CDD:277359	154/295 (52%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.770