DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpN58A and PPT1

DIOPT Version :9

Sequence 1:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_011639.3	Gene:	PPT1 / 853023	SGDID:	S000003355	Length:	513	Species:	Saccharomyces cerevisiae

Alignment Length:	304	Identity:	104/304 - (34%)
Similarity:	157/304 - (51%)	Gaps:	23/304 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 KKLLSNGSNKNKTLKFDEGINLDQIIAKLKLIGEIGSVVQISVREIEAVCSRAREVLLKQPTLLE 67
            |........||.:.:|     :.:::..|.|.|:     .:..:.:.|:.|.|..:..::|:::|
Yeast   179 KNAFKGAKIKNMSQEF-----ISKMVNDLFLKGK-----YLPKKYVAAIISHADTLFRQEPSMVE 233

  Fly    68 I------PAPINLLGDIHGQY---LNLLRYFESNGYPPDSVYLLLGDYVDRGKQSIETLTLLLAL 123
            :      ...|::.||.|||:   |||.|.|...|  |...||..||:||||..|.|...|...|
Yeast   234 LENNSTPDVKISVCGDTHGQFYDVLNLFRKFGKVG--PKHTYLFNGDFVDRGSWSCEVALLFYCL 296

  Fly   124 KARYPTKFYLLRGNHECSSINHFYGFYDECKRRYTVKLWRTFVDCYNCLPLAAIIEENIFCCHGG 188
            |..:|..|:|.|||||..::|..|||.||||.:|:.:::..|...:..||||.:|..:....|||
Yeast   297 KILHPNNFFLNRGNHESDNMNKIYGFEDECKYKYSQRIFNMFAQSFESLPLATLINNDYLVMHGG 361

  Fly   189 L-SPHLFSMQQIREIRRPIEIPESGLICDILWSDPDLRIMGWGPNERGVSHTFGSDVVSAFLHRF 252
            | |....::...:.|.|..:.|..|...::||:||. ...|.||::||:.|.||.|:...||...
Yeast   362 LPSDPSATLSDFKNIDRFAQPPRDGAFMELLWADPQ-EANGMGPSQRGLGHAFGPDITDRFLRNN 425

  Fly   253 KLNLICRGHQVVEDGYEFFAKRQLITIFSAPNYCGEFDNAGAMM 296
            ||..|.|.|::...|.:|..|.:|:|:|||||||....|.|.::
Yeast   426 KLRKIFRSHELRMGGVQFEQKGKLMTVFSAPNYCDSQGNLGGVI 469

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	100/285 (35%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	100/284 (35%)
PPT1	NP_011639.3	PLN03088	10..>130	CDD:215568
		TPR repeat	12..40	CDD:276809
		TPR repeat	45..75	CDD:276809
		TPR repeat	80..108	CDD:276809
		MPP_PP5_C	165..508	CDD:277362	104/304 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900