DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpN58A and Ppp1ca

DIOPT Version :9

Sequence 1:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_113715.1	Gene:	Ppp1ca / 24668	RGDID:	3375	Length:	330	Species:	Rattus norvegicus

Alignment Length:	294	Identity:	188/294 - (63%)
Similarity:	237/294 - (80%)	Gaps:	2/294 - (0%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 EGINLDQIIAKLKLI--GEIGSVVQISVREIEAVCSRAREVLLKQPTLLEIPAPINLLGDIHGQY 82
            |.:|||.||.:|..:  ...|..||::..||..:|.::||:.|.||.|||:.||:.:.|||||||
  Rat     5 EKLNLDSIIGRLLEVQGSRPGKNVQLTENEIRGLCLKSREIFLSQPILLELEAPLKICGDIHGQY 69

  Fly    83 LNLLRYFESNGYPPDSVYLLLGDYVDRGKQSIETLTLLLALKARYPTKFYLLRGNHECSSINHFY 147
            .:|||.||..|:||:|.||.|||||||||||:||:.||||.|.:||..|:||||||||:|||..|
  Rat    70 YDLLRLFEYGGFPPESNYLFLGDYVDRGKQSLETICLLLAYKIKYPENFFLLRGNHECASINRIY 134

  Fly   148 GFYDECKRRYTVKLWRTFVDCYNCLPLAAIIEENIFCCHGGLSPHLFSMQQIREIRRPIEIPESG 212
            ||||||||||.:|||:||.||:||||:|||::|.||||||||||.|.||:|||.|.||.::|:.|
  Rat   135 GFYDECKRRYNIKLWKTFTDCFNCLPIAAIVDEKIFCCHGGLSPDLQSMEQIRRIMRPTDVPDQG 199

  Fly   213 LICDILWSDPDLRIMGWGPNERGVSHTFGSDVVSAFLHRFKLNLICRGHQVVEDGYEFFAKRQLI 277
            |:||:||||||..:.|||.|:||||.|||::||:.|||:..|:||||.||||||||||||||||:
  Rat   200 LLCDLLWSDPDKDVQGWGENDRGVSFTFGAEVVAKFLHKHDLDLICRAHQVVEDGYEFFAKRQLV 264

  Fly   278 TIFSAPNYCGEFDNAGAMMCINQDLLCTFRVQRP 311
            |:|||||||||||||||||.:::.|:|:|::.:|
  Rat   265 TLFSAPNYCGEFDNAGAMMSVDETLMCSFQILKP 298

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	186/290 (64%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	186/289 (64%)
Ppp1ca	NP_113715.1	MPP_PP1_PPKL	8..298	CDD:277359	186/289 (64%)
Ppp1ca	NP_113715.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	306..330
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0639
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53795
OrthoDB	1	1.010	-	-		D327461at33208
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11668
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	7.930