DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment PpN58A and pef-1

DIOPT Version :9

Sequence 1:	NP_477384.1	Gene:	PpN58A / 37493	FlyBaseID:	FBgn0025573	Length:	324	Species:	Drosophila melanogaster
Sequence 2:	NP_741091.1	Gene:	pef-1 / 175257	WormBaseID:	WBGene00003969	Length:	707	Species:	Caenorhabditis elegans

Alignment Length:	333	Identity:	104/333 - (31%)
Similarity:	158/333 - (47%)	Gaps:	47/333 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     2 MKKLLSNGS---------NKNKTLKFDEGINLDQ-IIAKLKLIGEIGSVVQISVREIEAVCSRAR 56
            :||:|.:.|         .|..||    .:.||: .:||:....::..|  :..:.:..:...||
Worm   173 VKKMLEDTSPTNVDIDRNYKGPTL----SLPLDKPQVAKMIEAFKVNKV--LHPKYVLMILHEAR 231

  Fly    57 EVLLKQPTLLEIPAPIN----LLGDIHGQYLNLLRYFESNGYPP-DSVYLLLGDYVDRGKQSIET 116
            ::....|::..|...|:    :.||:||::.:|......||||. |:.|:..||:||||.||||.
Worm   232 KIFKAMPSVSRISTSISNQVTICGDLHGKFDDLCIILYKNGYPSVDNPYIFNGDFVDRGGQSIEV 296

  Fly   117 LTLLLALKARYPTKFYLLRGNHECSSINHFYGFYDECKRRY---TVKLWRTFVDCYNCLPLAAII 178
            |.:|.||....|...||.|||||...:|..|||..|...:|   :..:.|...|.::.||:|.||
Worm   297 LCVLFALVIVDPMSIYLNRGNHEDHIMNLRYGFIKELSTKYKDLSTPITRLLEDVFSWLPIATII 361

  Fly   179 EENIFCCHGGLSPHL-------FSMQQIREIRRP--------------IEIPESGLICDILWSDP 222
            :.:||..|||:|...       ....:.:.:.||              :.:.|...:.||:||||
Worm   362 DRDIFVVHGGISDQTEVSKLDKIPRHRFQSVLRPPVNKGMESEKENSAVNVDEWKQMLDIMWSDP 426

  Fly   223 DLRIMGWGPNE-RGVSHTFGSDVVSAFLHRFKLNLICRGHQVVEDGYEFFAKRQLITIFSAPNYC 286
            ......| ||. ||....||:|:.::||.:....|:.|.|:...:||||......:|:|||.||.
Worm   427 KQNKGCW-PNVFRGGGSYFGADITASFLEKHGFRLLVRSHECKFEGYEFSHNNTCLTVFSASNYY 490

  Fly   287 GEFDNAGA 294
            ....|.||
Worm   491 ETGSNRGA 498

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
PpN58A	NP_477384.1	PTZ00480	22..311	CDD:185658	97/304 (32%)
PpN58A	NP_477384.1	MPP_superfamily	23..311	CDD:301300	97/303 (32%)
pef-1	NP_741091.1	MPP_RdgC	199..515	CDD:277364	97/303 (32%)
		PP2Ac	218..514	CDD:197547	92/282 (33%)
		EFh	634..699	CDD:238008
		EF-hand_7	634..698	CDD:290234
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000018
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000