Protein Alignment CG9294 and TMPRSS4

DIOPT Version :10

• Sequence 1: NP_995920.1
• Gene: CG9294 / 37491
• FlyBaseID: FBgn0034666
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: XP_005271670.1
• Gene: TMPRSS4 / 56649
• HGNCID: 11878
• Length: 494
• Species: Homo sapiens
• Alignment Length: 308
• Identity: 99/308 - (32%)
• Similarity: 148/308 - (48%)
• Gaps: 58/308 - (18%)

  Fly    62 TTTSSTTSRTTTSRTTVANFPIERDCVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYC 126
            |..|.......:|...::...:...|:.|...|...  ::||.:|..|..:||...|....:..|
Human   168 TENSQELRMRNSSGPCLSGSLVSLHCLACGKSLKTP--RVVGVEEASVDSWPWQVSIQYDKQHVC 230

  Fly   127 SGSLINDLYVLTAAHCVEGVPPELITLRFLEH------------NRSHSNDDIVIQRYVSRVKVH 179
            .||:::..:|||||||            |.:|            ::..|...:.:.:.:. ::.:
Human   231 GGSILDPHWVLTAAHC------------FRKHTDVFNWKVRAGSDKLGSFPSLAVAKIII-IEFN 282

  Fly   180 ELYNPRSFDNDLAVLRLNQPLDMRHHRLRPICLPVQSYSFDHELG-----IVAGWG-AQREGGFG 238
            .:| |:  |||:|:::|..||.. ...:||||||.    ||.||.     .:.||| .::.||..
Human   283 PMY-PK--DNDIALMKLQFPLTF-SGTVRPICLPF----FDEELTPATPLWIIGWGFTKQNGGKM 339

  Fly   239 TDTLREVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQY 303
            :|.|.:..|.|:..:.|.....|: |::|:.||||| |.|||.|.|.|||||||.    .|..|:
Human   340 SDILLQASVQVIDSTRCNADDAYQ-GEVTEKMMCAG-IPEGGVDTCQGDSGGPLM----YQSDQW 398

  Fly   304 QLAGIVSWGVGCARPQSPGVYTRVNQYLRWL-----------GSNTPG 340
            .:.||||||.||..|.:|||||:|:.||.|:           ..|:||
Human   399 HVVGIVSWGYGCGGPSTPGVYTKVSAYLNWIYNVWKDRTIQRSCNSPG 446

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	89/250 (36%)
TMPRSS4	XP_005271670.1	LDLa	58..92	CDD:238060
		SRCR_2	108..197	CDD:470597	4/28 (14%)
		Tryp_SPc	204..429	CDD:214473	89/251 (35%)