DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9294 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_995920.1	Gene:	CG9294 / 37491	FlyBaseID:	FBgn0034666	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_056590.2	Gene:	Tmprss2 / 50528	MGIID:	1354381	Length:	490	Species:	Mus musculus

Alignment Length:	262	Identity:	80/262 - (30%)
Similarity:	124/262 - (47%)	Gaps:	33/262 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 CVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAHCVE------- 144
            |:.|....:....:||||.......:||...:.:.....|.||:|...:::|||||||
Mouse   240 CIECGVRSVKRQSRIVGGLNASPGDWPWQVSLHVQGVHVCGGSIITPEWIVTAAHCVEEPLSSPR 304

  Fly   145 ------GVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMR 203
                  |:..:.:......|.             |.:|..|..|:.::.:||:|:::|..||..
Mouse   305 YWTAFAGILRQSLMFYGSRHQ-------------VEKVISHPNYDSKTKNNDIALMKLQTPLAF- 355

  Fly   204 HHRLRPICLPVQSYSFDHELGI-VAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQIT 267
            :..::|:|||......|.:... ::||||..|.|..:|.|....|.::..|:|.:...|. ..||
Mouse   356 NDLVKPVCLPNPGMMLDLDQECWISGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYN-NLIT 419

  Fly   268 DNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLR 332
            ..|:|||:: :|..|:|.|||||||.|.   :.|.:.|.|..|||.|||:...||||..|..:..
Mouse   420 PAMICAGFL-QGSVDSCQGDSGGPLVTL---KNGIWWLIGDTSWGSGCAKALRPGVYGNVTVFTD 480

  Fly   333 WL 334
            |:
Mouse   481 WI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	100..333	CDD:214473	77/246 (31%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	77/246 (31%)
Tmprss2	NP_056590.2	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:373897	2/6 (33%)
		Tryp_SPc	254..485	CDD:238113	78/248 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm11120
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910