Protein Alignment CG9294 and KLK2

DIOPT Version :10

• Sequence 1: NP_995920.1
• Gene: CG9294 / 37491
• FlyBaseID: FBgn0034666
• Length: 352
• Species: Drosophila melanogaster
• Sequence 2: NP_005542.1
• Gene: KLK2 / 3817
• HGNCID: 6363
• Length: 261
• Species: Homo sapiens
• Alignment Length: 264
• Identity: 79/264 - (29%)
• Similarity: 117/264 - (44%)
• Gaps: 63/264 - (23%)

  Fly   100 KIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAHCVEGVPPELITLRFLEHNRSHSN 164
            :||||.|...|..||...:..:...:|.|.|::..:|||||||::                  .|
Human    24 RIVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLK------------------KN 70

  Fly   165 DDIVIQRY-------------VSRVKVHELYN-----------PRSFDNDLAVLRLNQPLDMRHH 205
            ..:.:.|:             ||....|.|||           .....:||.:|||::|..:. .
Human    71 SQVWLGRHNLFEPEDTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKIT-D 134

  Fly   206 RLRPICLPVQSYSFDHELG---IVAGWGA-QREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQI 266
            .::.:.||.|    :..||   ..:|||: :.|......:|:.|.:.:|....|....:.:   :
Human   135 VVKVLGLPTQ----EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEK---V 192

  Fly   267 TDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWG-VGCARPQSPGVYTRVNQY 330
            |:.|:||| :..||||.|.|||||||...     |..|  ||.||| ..||.|:.|.|||:|..|
Human   193 TEFMLCAG-LWTGGKDTCGGDSGGPLVCN-----GVLQ--GITSWGPEPCALPEKPAVYTKVVHY 249

  Fly   331 LRWL 334
            .:|:
Human   250 RKWI 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	78/261 (30%)
KLK2	NP_005542.1	Tryp_SPc	25..256	CDD:238113	79/263 (30%)