DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9294 and Tmprss11b

DIOPT Version :9

Sequence 1:	NP_995920.1	Gene:	CG9294 / 37491	FlyBaseID:	FBgn0034666	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	NP_795998.2	Gene:	Tmprss11b / 319875	MGIID:	2442893	Length:	416	Species:	Mus musculus

Alignment Length:	293	Identity:	94/293 - (32%)
Similarity:	140/293 - (47%)	Gaps:	43/293 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 SSTTSRTTTSRTTVANFPIERDCVTCRCG----LINTLYKIVGGQETRVHQYPWMAVILIYNRFY 125
            |.||...:...|.::....|: .:..|||    :..|..:|.||......::||.|.:.:..:.|
Mouse   146 SLTTDPGSLKLTEISKVDAEK-IINNRCGRRPRMSATYDRITGGSTAHKGEWPWQASLRVNGKHY 209

  Fly   126 CSGSLINDLYVLTAAHCVEGV--PPEL-------ITLRFLEHNRSHSNDDIVIQRYVSRVKVHEL 181
            |..|||.:.::||||||.:|.  |..|       :|..:::|:             |..:.:||.
Mouse   210 CGASLIGERFLLTAAHCFQGTNNPKNLTVSFGTRVTPAYMQHS-------------VQEIIIHED 261

  Fly   182 YNPRSFDNDLAVLRLNQPLDMRH--HRLRPICLPVQSYSFDHELG-IVAGWGAQREGGFGTDTLR 243
            |......:|:||::|.:.:...:  ||   :|||..:..|....| :|.|||:....|.....|:
Mouse   262 YVKGEHHDDVAVIKLTEKVSFNNDVHR---VCLPESTQIFPPGEGVVVTGWGSFSYNGKSPLLLQ 323

  Fly   244 EVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQ---YQL 305
            :..:.::..:.|.:...| .|:|.|.|:||||: ||..|||.|||||||     ..|..   :.|
Mouse   324 KASIKIIDTNTCNSEEAY-GGRIVDTMLCAGYL-EGSIDACQGDSGGPL-----VHPNSRDIWYL 381

  Fly   306 AGIVSWGVGCARPQSPGVYTRVNQYLRWLGSNT 338
            .||||||..|.|...||||.||..|..|:.|.|
Mouse   382 VGIVSWGHECGRVNKPGVYMRVTSYRNWIASKT 414

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	100..333	CDD:214473	82/247 (33%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	82/247 (33%)
Tmprss11b	NP_795998.2	SEA	46..140	CDD:279699
		Tryp_SPc	184..410	CDD:214473	82/248 (33%)
		Tryp_SPc	185..413	CDD:238113	83/250 (33%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	179	1.000	Inparanoid score	I3995
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.960