DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9294 and Tmprss6

DIOPT Version :9

Sequence 1:	NP_995920.1	Gene:	CG9294 / 37491	FlyBaseID:	FBgn0034666	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_006242057.1	Gene:	Tmprss6 / 315388	RGDID:	1307138	Length:	811	Species:	Rattus norvegicus

Alignment Length:	251	Identity:	109/251 - (43%)
Similarity:	150/251 - (59%)	Gaps:	16/251 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    90 CRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAHCVEG---VPPELI 151
            |.|||.....:||||..:...::||.|.:.|..|..|.|:||.|.:|:|||||.:.   ..|.|.
  Rat   566 CDCGLQGPSSRIVGGAMSSEGEWPWQASLQIRGRHICGGALIADRWVITAAHCFQEDSMASPRLW 630

  Fly   152 TLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMRHHRLRPICLPVQS 216
            |: ||...|.:|.....:...|||:.:|..:...|.|.|:|:|:|:.|: :....:||:|||.:|
  Rat   631 TV-FLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLDHPV-VYSATVRPVCLPARS 693

  Fly   217 YSFDHELG---IVAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQITDNMMCAGYISE 278
            :.|  |.|   .:.|||||||||.|:.||::|||.::||..|.....|   |:|..|:|||| .:
  Rat   694 HFF--EPGQHCWITGWGAQREGGPGSSTLQKVDVQLIPQDLCNEAYRY---QVTPRMLCAGY-RK 752

  Fly   279 GGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLRWL 334
            |.||||.|||||||  ...|..|::.|||:||||:||.||...||||||.:.:.|:
  Rat   753 GKKDACQGDSGGPL--VCKEPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVVNWI 806

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	100..333	CDD:214473	104/238 (44%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	104/238 (44%)
Tmprss6	XP_006242057.1	SEA	88..185	CDD:279699
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:278486	109/251 (43%)
		Tryp_SPc	576..806	CDD:214473	104/239 (44%)
		Tryp_SPc	577..809	CDD:238113	105/240 (44%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BJ04
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810