DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG9294 and Tmprss2

DIOPT Version :9

Sequence 1:	NP_995920.1	Gene:	CG9294 / 37491	FlyBaseID:	FBgn0034666	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_008766769.1	Gene:	Tmprss2 / 156435	RGDID:	620766	Length:	580	Species:	Rattus norvegicus

Alignment Length:	263	Identity:	82/263 - (31%)
Similarity:	124/263 - (47%)	Gaps:	35/263 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    87 CVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAHCVE------- 144
            |:.|....:....:||||.......:||...:.:.....|.||:|...:::|||||||
  Rat   240 CIECGVRSVRRQSRIVGGSTASPGDWPWQVSLHVQGIHVCGGSIITPEWIVTAAHCVEEPLSSPR 304

  Fly   145 ------GVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMR 203
                  |:..:.:......|.             |.:|..|..|:.::.:||:|:::|..||..
  Rat   305 YWTAFAGILKQSLMFYGSRHQ-------------VEKVISHPNYDSKTKNNDIALMKLQTPLAF- 355

  Fly   204 HHRLRPICLPVQSYSFD--HELGIVAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQI 266
            :..::|:|||......|  .|..| :||||..|.|..:|.|....|.::..|:|.:...|. ..|
  Rat   356 NDVVKPVCLPNPGMMLDLAQECWI-SGWGATYEKGKTSDVLNAAMVPLIEPSKCNSKYIYN-NLI 418

  Fly   267 TDNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYL 331
            |..|:|||:: :|..|:|.|||||||.|..:|   .:.|.|..|||.|||:...||||..|..:.
  Rat   419 TPAMICAGFL-QGSVDSCQGDSGGPLVTLKNE---IWWLIGDTSWGSGCAKAYRPGVYGNVTVFT 479

  Fly   332 RWL 334
            .|:
  Rat   480 DWI 482

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	100..333	CDD:214473	79/247 (32%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	79/247 (32%)
Tmprss2	XP_008766769.1	LDLa	112..147	CDD:238060
		SRCR_2	152..247	CDD:292133	2/6 (33%)
		Tryp_SPc	253..482	CDD:214473	79/248 (32%)
		Tryp_SPc	254..485	CDD:238113	80/249 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	178	1.000	Inparanoid score	I3918
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm45531
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.960