DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG9294 and tmprss6

DIOPT Version :9

Sequence 1:	NP_995920.1	Gene:	CG9294 / 37491	FlyBaseID:	FBgn0034666	Length:	352	Species:	Drosophila melanogaster
Sequence 2:	XP_004913946.2	Gene:	tmprss6 / 100489045	XenbaseID:	XB-GENE-1011573	Length:	806	Species:	Xenopus tropicalis

Alignment Length:	266	Identity:	90/266 - (33%)
Similarity:	145/266 - (54%)	Gaps:	11/266 - (4%)

- Green bases have known domain annotations that are detailed below.

  Fly    77 TVANFPIERDCVTCRCGLINTLYKIVGGQETRVHQYPWMAVILIYNRFYCSGSLINDLYVLTAAH 141
            ::|:.|...|...|.||:.....::|||.:.:..::||.|.:.:.....|.|:|:.|.::|||||
Frog   547 SIADCPDGSDENNCGCGIQAVGIRLVGGTQAQEGEWPWQASLQVRGEHICGGTLVADQWILTAAH 611

  Fly   142 CV---EGVPPELITLRFLEHNRSHSNDDIVIQRYVSRVKVHELYNPRSFDNDLAVLRLNQPLDMR 203
            |.   ....||:.|: :|...|...:....:...|.|:.:|..|:..|.|.|:|::.|:..:.:.
Frog   612 CFTPESYASPEVWTV-YLGKVRLSRSTQKELAFKVIRLVIHPFYDEDSHDYDVALVLLDHLVPLT 675

  Fly   204 HHRLRPICLPVQSYSFDHELGI-VAGWGAQREGGFGTDTLREVDVVVLPQSECRNGTTYRPGQIT 267
            ...::|||||..::.|...... |.|||:.:|.|..:|.|::||:.::.|..|.....|   ||:
Frog   676 SPHVQPICLPSSTHHFPTGSSCWVTGWGSVKENGPTSDVLQKVDIQLVAQDICTELYRY---QIS 737

  Fly   268 DNMMCAGYISEGGKDACSGDSGGPLQTTFDEQPGQYQLAGIVSWGVGCARPQSPGVYTRVNQYLR 332
            ..|:|||| .:|.||||.||||.||  ......|::..||:||||.||..|:..|||:|:.:.::
Frog   738 PRMLCAGY-RDGSKDACQGDSGSPL--VCKTASGRWFQAGLVSWGAGCGIPRYFGVYSRITRLVQ 799

  Fly   333 WLGSNT 338
            |:.|.|
Frog   800 WIESIT 805

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG9294	NP_995920.1	Tryp_SPc	100..333	CDD:214473	81/236 (34%)
CG9294	NP_995920.1	Tryp_SPc	101..334	CDD:238113	81/236 (34%)
tmprss6	XP_004913946.2	SEA	77..176	CDD:396113
		CUB	235..303	CDD:412131
		LDLa	448..478	CDD:238060
		LDLa	480..514	CDD:238060
		LDLa	525..560	CDD:238060	3/12 (25%)
		Tryp_SPc	572..804	CDD:238113	82/238 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.910