Protein Alignment CG4372 and AGA

DIOPT Version :10

• Sequence 1: NP_611615.1
• Gene: CG4372 / 37490
• FlyBaseID: FBgn0034665
• Length: 397
• Species: Drosophila melanogaster
• Sequence 2: NP_000018.2
• Gene: AGA / 175
• HGNCID: 318
• Length: 346
• Species: Homo sapiens
• Alignment Length: 323
• Identity: 129/323 - (39%)
• Similarity: 195/323 - (60%)
• Gaps: 9/323 - (2%)

  Fly    54 LLISTWNYTDANLQAWSVLQQGPRRTRQAVIQGCMACQNQRCGRLLTGRSSPDTEGALTLEAAIM 118
            |:::||.:.:|...||..|..| .....||..||..|:.::|...:....|||..|..||:|.||
Human    29 LVVNTWPFKNATEAAWRALASG-GSALDAVESGCAMCEREQCDGSVGFGGSPDELGETTLDAMIM 92

  Fly   119 DGESLEYGAVAGMNGVRNAILVADAVLKYTKHSVLVGKSATKFARSLGYKEEYLTDARTRNVLKK 183
            ||.:::.|||..:..::|||.||..||::|.|::|||:|||.||:|:|:..|.|:...::.:...
Human    93 DGTTMDVGAVGDLRRIKNAIGVARKVLEHTTHTLLVGESATTFAQSMGFINEDLSTTASQALHSD 157

  Fly   184 WRSNGCQPNFWRDVHPSPAENCGPYSPLPEHMHQH-PMHQEYAIIQGQHDQLAFLALDAEGKFHV 247
            |.:..||||:||:|.|.|::.||||.| |..:.|. |:|:|....:| ||.:..:.:...|....
Human   158 WLARNCQPNYWRNVIPDPSKYCGPYKP-PGILKQDIPIHKETEDDRG-HDTIGMVVIHKTGHIAA 220

  Fly   248 ASQSSGAQFRIPGRVGDSAVPGAGIYADNEVGGAVASGDGDVLMRHLPAFLAVEAMRAGKEPDKA 312
            .:.::|.:|:|.||||||.:||||.|||:..|.|.|:|:||:|||.||::.|||.||.|::|..|
Human   221 GTSTNGIKFKIHGRVGDSPIPGAGAYADDTAGAAAATGNGDILMRFLPSYQAVEYMRRGEDPTIA 285

  Fly   313 AELVVQRLLRHNTEFNGAVVVVNRRGIYAAACAGLD---EFHFVVSGGKEYLSMARVERVKCL 372
            .:.|:.|:.:|..||.|||:..|..|.|.|||..|.   :|.|:|...::  :....|:|.|:
Human   286 CQKVISRIQKHFPEFFGAVICANVTGSYGAACNKLSTFTQFSFMVYNSEK--NQPTEEKVDCI 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG4372	NP_611615.1	Glycosylasparaginase	54..356	CDD:271335	126/305 (41%)
AGA	NP_000018.2	Glycosylasparaginase	29..332	CDD:271335	126/305 (41%)