Protein Alignment tpr and KLK4

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_004908.4
• Gene: KLK4 / 9622
• HGNCID: 6365
• Length: 254
• Species: Homo sapiens
• Alignment Length: 242
• Identity: 80/242 - (33%)
• Similarity: 129/242 - (53%)
• Gaps: 24/242 - (9%)

  Fly   126 RIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKERISVRLLEHDRKMSH 190
            :|:.|::...|..||.|.|:.....:|:..|::.|::|:|:||........:.:..||.|::..
Human    30 QIINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQEPG- 93

  Fly   191 MQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCM----PTPGRSFKGENGIVT 251
            .|.::..::  :.||:||.....||:.:|||||.|..::.:..:.:    ||.|.|.     :|:
Human    94 SQMVEASLS--VRHPEYNRPLLANDLMLIKLDESVSESDTIRSISIASQCPTAGNSC-----LVS 151

  Fly   252 GWGALKVGG-PTSDTLQEVQVPILSQDECRKSRYGNKITDNMLCGGYDEGGKDSCQGDSGGPLHI 315
            |||.|..|. ||  .||.|.|.::|::.|.| .|......:|.|.|..:..||||.|||||||
Human   152 GWGLLANGRMPT--VLQCVNVSVVSEEVCSK-LYDPLYHPSMFCAGGGQDQKDSCNGDSGGPL-- 211

  Fly   316 VASGTREHQIAGVVSWGEG-CAKAGYPGVYARVNRYGTWIKNLTKQA 361
            :.:|    .:.|:||:|:. |.:.|.||||..:.::..||:. |.||
Human   212 ICNG----YLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEK-TVQA 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	77/234 (33%)
KLK4	NP_004908.4	Tryp_SPc	31..250	CDD:238113	77/236 (33%)