Protein Alignment tpr and PRSS27

DIOPT Version :9

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_114154.1
• Gene: PRSS27 / 83886
• HGNCID: 15475
• Length: 290
• Species: Homo sapiens
• Alignment Length: 260
• Identity: 93/260 - (35%)
• Similarity: 144/260 - (55%)
• Gaps: 30/260 - (11%)

  Fly   118 CGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFR--KERISVR 180
            ||...:..|:||||:|:..::||...:...|..:|..||:.:|::|||:||   ||  .|....:
Human    26 CGRPRMLNRMVGGQDTQEGEWPWQVSIQRNGSHFCGGSLIAEQWVLTAAHC---FRNTSETSLYQ 87

  Fly   181 LLEHDRKMSH--MQKIDRKVAEVITHPKYNARNYDNDIAIIKLDEPVEFNEVLHPVCMPTPGRSF 243
            :|...|::..  ...:..:|.:|.::|.|.......|:|:::|:.||.|...:.|||:|.|...|
Human    88 VLLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLPDPSVIF 152

  Fly   244 K-GENGIVTGWGALKVGGPTSD-------TLQEVQVPILSQDEC-----RKSRYG---NKITDNM 292
            : |.|..|||||:     |:.:       .||::.|||:...:|     :.:.:|   ..|.::|
Human   153 ETGMNCWVTGWGS-----PSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKTIKNDM 212

  Fly   293 LCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYGTWIKNL 357
            ||.|::||.||:|:||||||| :...|....| |||:|||||||:...||||.||..:..||..:
Human   213 LCAGFEEGKKDACKGDSGGPL-VCLVGQSWLQ-AGVISWGEGCARQNRPGVYIRVTAHHNWIHRI 275

  Fly   358  357
            Human   276  275

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	89/247 (36%)
		Tryp_SPc	127..356	CDD:238113	90/248 (36%)
PRSS27	NP_114154.1	Tryp_SPc	34..272	CDD:214473	89/247 (36%)
		Tryp_SPc	36..275	CDD:238113	90/248 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D380103at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100031
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.820