DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment tpr and gzma

DIOPT Version :9

Sequence 1:NP_611611.1 Gene:tpr / 37486 FlyBaseID:FBgn0034661 Length:372 Species:Drosophila melanogaster
Sequence 2:XP_001335166.1 Gene:gzma / 795070 ZFINID:ZDB-GENE-091204-156 Length:257 Species:Danio rerio


Alignment Length:261 Identity:77/261 - (29%)
Similarity:124/261 - (47%) Gaps:46/261 - (17%)


- Green bases have known domain annotations that are detailed below.


  Fly   113 CSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLLTASHCVYGFRKE-- 175
            |||.         .||||::.: ....|:..:.......|...|::.:::|||:||     ||  
Zfish    23 CSDV---------SIVGGKDVK-KALSWMVSIQVNQNHKCGGILIHKEWVLTAAHC-----KEDS 72

  Fly   176 RISVRLLEHDRKMSHMQKIDRKVA----EVITHPK-YNARNYDNDIAIIKLDEPVEFNEVLHPVC 235
            ..||.:|.....:|   |..:::|    |:   |: :|.:...:||.:|:|.:.|:    ..|..
Zfish    73 YSSVTVLIGSLSLS---KGSQRIAIHNYEI---PETFNKKTKKDDIMLIRLSKKVK----AKPYK 127

  Fly   236 MPTPGRSFK-GENGIVTGWGALKV-GGPTSDTLQEVQVPILSQDECRKSRYGNK---ITDNMLCG 295
            :|...:..: |...:|.|||.... |...||.||.::|.::.:.:|  :||.|:   ||.:|||.
Zfish   128 IPKKEKDVQPGTKCVVRGWGTTDYKGKQASDKLQMLEVLVVDRVQC--NRYYNRNPVITKDMLCA 190

  Fly   296 GYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVN-RYGTWIKNLTK 359
            |..:..:.:|.|||||||..      |..:.||:|...||.....|.||..:: |:.|||..:.|
Zfish   191 GNTQQHRGTCLGDSGGPLEC------EKNLVGVLSGSHGCGDPKKPTVYTLLSKRHITWINKILK 249

  Fly   360 Q 360
            |
Zfish   250 Q 250

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
tprNP_611611.1 Tryp_SPc 126..354 CDD:214473 70/240 (29%)
Tryp_SPc 127..356 CDD:238113 72/241 (30%)
gzmaXP_001335166.1 Tryp_SPc 28..247 CDD:238113 72/242 (30%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C170587744
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
10.930

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