Protein Alignment tpr and Tmprss12

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_898932.2
• Gene: Tmprss12 / 75002
• MGIID: 1922252
• Length: 336
• Species: Mus musculus
• Alignment Length: 278
• Identity: 81/278 - (29%)
• Similarity: 138/278 - (49%)
• Gaps: 20/278 - (7%)

  Fly    98 RATTPAPPTLNPPRNCSDCVCGIANIQ-----KRIVGGQETEVHQYPW-VAMLLYGG---RFYCA 153
            :||.|.||....|....   ||||.::     .||:||.:.:...:|| |::.:..|   ...|.
Mouse    35 QATVPGPPEEEQPVTKD---CGIAPLRGAVEGSRIIGGSQADTGAWPWQVSLQVQDGDILMHVCG 96

  Fly   154 ASLLNDQFLLTASHCVYGFR---KERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDND 215
            .:|:.|:::|||:||....|   |.|..:...:..|...|.:.|  ::.::|..|.:....:.||
Mouse    97 GALVRDRWVLTAAHCTKEARDPLKWRAVMGTNDLTRSPYHSRNI--RITDIIIPPDFIMETFVND 159

  Fly   216 IAIIKLDEPVEFNEVLHPVCMPTPGRSFKGENG--IVTGWGALKVGGPTSDTLQEVQVPILSQDE 278
            ||:.:|...|.:|:.:.|:|:|........:|.  .::|||..:..|..:..|||.:|..:|::.
Mouse   160 IALFRLKRAVRYNDYIQPICLPFGVFQKLDQNTACFISGWGRTREEGNGTTILQEAKVHFISREV 224

  Fly   279 CRKSR-YGNKITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPG 342
            |...: |...|.:...|.|::.|..|||:|||||||.........:.:.|:.|:|.||.:..:||
Mouse   225 CSSDQGYSGMIPNTSFCAGHENGTFDSCRGDSGGPLMCYLPEHSRYFVMGITSYGHGCGRRHFPG 289

  Fly   343 VYARVNRYGTWIKNLTKQ 360
            ||:..:.:..|:.:...|
Mouse   290 VYSNPSFFQEWMTHYLSQ 307

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	69/238 (29%)
Tmprss12	NP_898932.2	Tryp_SPc	66..300	CDD:238113	68/235 (29%)