Protein Alignment tpr and TPSAB1

DIOPT Version :9

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_003285.2
• Gene: TPSAB1 / 7177
• HGNCID: 12019
• Length: 275
• Species: Homo sapiens
• Alignment Length: 274
• Identity: 95/274 - (34%)
• Similarity: 142/274 - (51%)
• Gaps: 35/274 - (12%)

  Fly    96 TRRATTPAPPTLNPPRNCSDCVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRF---YCAASLL 157
            :|....|||              |.|..:..||||||....::||...|...|.:   :|..||:
Human    14 SRAYAAPAP--------------GQALQRVGIVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLI 64

  Fly   158 NDQFLLTASHCVYGFRKERISVRLLEHDRKMSHMQKIDRKVAEVITHPKYNARNYDNDIAIIKLD 222
            :.|::|||:|||....|:..::|:...::.:.:..:: ..|:.:|.||::.......|||:::|:
Human    65 HPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQL-LPVSRIIVHPQFYTAQIGADIALLELE 128

  Fly   223 EPVEFNEVLHPVCMPTPGRSF-KGENGIVTGWGALKVGG--PTSDTLQEVQVPILSQDECRKSRY 284
            |||..:..:|.|.:|....:| .|....|||||.:....  |....|::|:|||:....| .::|
Human   129 EPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHIC-DAKY 192

  Fly   285 ------GNK---ITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGY 340
                  |:.   :.|:|||.|...  :|||||||||||....:||...  |||||||||||:...
Human   193 HLGAYTGDDVRIVRDDMLCAGNTR--RDSCQGDSGGPLVCKVNGTWLQ--AGVVSWGEGCAQPNR 253

  Fly   341 PGVYARVNRYGTWI 354
            ||:|.||..|..||
Human   254 PGIYTRVTYYLDWI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	126..354	CDD:214473	87/242 (36%)
		Tryp_SPc	127..356	CDD:238113	89/243 (37%)
TPSAB1	NP_003285.2	Tryp_SPc	31..268	CDD:238113	89/243 (37%)
		Tryp_SPc	31..267	CDD:214473	87/241 (36%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165152895
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X11
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	2.840