Protein Alignment tpr and Tmprss6

DIOPT Version :10

• Sequence 1: NP_611611.1
• Gene: tpr / 37486
• FlyBaseID: FBgn0034661
• Length: 372
• Species: Drosophila melanogaster
• Sequence 2: NP_082178.2
• Gene: Tmprss6 / 71753
• MGIID: 1919003
• Length: 811
• Species: Mus musculus
• Alignment Length: 266
• Identity: 98/266 - (36%)
• Similarity: 157/266 - (59%)
• Gaps: 18/266 - (6%)

  Fly   105 PTLNPPRNCSD------CVCGIANIQKRIVGGQETEVHQYPWVAMLLYGGRFYCAASLLNDQFLL 163
            |..:...:|.|      |.||:..:..|||||..:...::||.|.|...||..|..:|:.|::::
Mouse   549 PECDGQSDCRDGSDEQHCDCGLQGLSSRIVGGTVSSEGEWPWQASLQIRGRHICGGALIADRWVI 613

  Fly   164 TASHCVYGFRKERI-SVRL----LEHDRKMSHMQ-KIDRKVAEVITHPKYNARNYDNDIAIIKLD 222
            ||:||   |:::.: |.:|    |...|:.|... ::..||:.:..||.:...::|.|:|:::||
Mouse   614 TAAHC---FQEDSMASPKLWTVFLGKMRQNSRWPGEVSFKVSRLFLHPYHEEDSHDYDVALLQLD 675

  Fly   223 EPVEFNEVLHPVCMPTPGRSFK-GENGIVTGWGALKVGGPTSDTLQEVQVPILSQDECRKSRYGN 286
            .||.::..:.|||:|.....|: |::..:|||||.:.|||.|:|||:|.|.::.||.|.:: |..
Mouse   676 HPVVYSATVRPVCLPARSHFFEPGQHCWITGWGAQREGGPVSNTLQKVDVQLVPQDLCSEA-YRY 739

  Fly   287 KITDNMLCGGYDEGGKDSCQGDSGGPLHIVASGTREHQIAGVVSWGEGCAKAGYPGVYARVNRYG 351
            :::..|||.||.:|.||:||||||||| :....:....:||:||||.||.:..:.|||.||.|..
Mouse   740 QVSPRMLCAGYRKGKKDACQGDSGGPL-VCREPSGRWFLAGLVSWGLGCGRPNFFGVYTRVTRVI 803

  Fly   352 TWIKNL 357
            .||:.:
Mouse   804 NWIQQV 809

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
tpr	NP_611611.1	Tryp_SPc	127..356	CDD:238113	91/235 (39%)
Tmprss6	NP_082178.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..48
		SEA	88..182	CDD:460188
		LDLa	459..489	CDD:238060
		LDLa	495..525	CDD:238060
		Ldl_recept_a	529..566	CDD:395011	3/16 (19%)
		Tryp_SPc	577..809	CDD:238113	91/236 (39%)